SynthesisHuman factors2013
Examining the interaction of force and repetition on musculoskeletal disorder risk: a systematic literature review.
Synthesis in Human factors, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 65 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Cellular and Biocellular Therapy in Musculoskeletal Pain, Dysfunction, Degenerative or Inflammatory Disease
Adipose-Derived Biocellular Regenerative Therapy in Treatment of Osteoarthritis (OA) and Associated Connective Tissue Degeneration and Pain
Who cites it
65 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Transparency as a Means to Analyse the Impact of Inertial Sensors on Users during the Occupational Ergonomic Assessment: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- Overuse-Related Injuries of the Musculoskeletal System: Systematic Review and Quantitative Synthesis of Injuries, Locations, Risk Factors and Assessment Techniques.Sensors (Basel, Switzerland) · 2021Pooled it
- Towards High-Accuracy Athletic Injury Predictions Using a First-Principles Modelling Approach: Theory to (Future) Practice.Sports medicine (Auckland, N.Z.) · 2026Review
- Developing a Fundamental Theoretical Definition for Athletic Injury: Metaphysics, Logic, and Mathematics.Sports medicine (Auckland, N.Z.) · 2026Review
- Cyclic Mechanism Affects Lumbar Spine Creep Response.Annals of biomedical engineering · 2026Article
- A new conceptual framework for managing hamstring injury risk in soccer - implementing a data-informed approach: a narrative review.Biology of sport · 2026Review
- Article
- Occupational ergonomic research and contextual design execution of a new workstation to reduce work-related musculoskeletal disorders (WRMSDs) among Dhokra handicraft artisans: an unorganized sector of India.Industrial health · 2025Article
- Musculoskeletal Health Effects of Manual Sandcrete Block Handling Among Construction Artisans: Implications for Industry Practice and Training.International journal of environmental research and public health · 2025Article
- The Natural History of Bone Stress Injuries in Athletes: From Inception to Resolution.Sports medicine (Auckland, N.Z.) · 2025Review
- Are There Sex Differences in Wrist Velocity and Forearm Muscle Activity When Performing Identical Hand-Intensive Work Tasks?Sensors (Basel, Switzerland) · 2025Article
- Mixed adverse ergonomic factors exposure in relation to work-related musculoskeletal disorders: a multicenter cross-sectional study of Chinese medical personnel.Scientific reports · 2025Article
- The effect of a soft active back support exosuit on trunk motion and thoracolumbar spine loading during squat and stoop lifts.Ergonomics · 2025Article
- Sustained acoustic medicine increases local circulation with a diclofenac delivery patch: a randomized placebo controlled study.Frontiers in medical technology · 2025Article
- Intravitreal Plungerless Injector Device (IPLID): An Innovative Intravitreal Injector Device.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Can back exosuits simultaneously increase lifting endurance and reduce musculoskeletal disorder risk?Wearable technologies · 2024Article
- The mechanical loading of the spine in physical activities.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Blocking CCN2 Reduces Established Bone Loss Induced by Prolonged Intense Loading by Increasing Osteoblast Activity in Rats.JBMR plus · 2023Article
- Prevalence of lower back pain and its associations with lifestyle behaviors among college students in Saudi Arabia.BMC musculoskeletal disorders · 2023Article
- Musculoskeletal-Modeling-Based, Full-Body Load-Assessment Tool for Ergonomists (MATE): Method Development and Proof of Concept Case Studies.International journal of environmental research and public health · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectiveOur aims were (a) to perform a systematic literature review of epidemiological studies that examined the interaction of force and repetition with respect to musculoskeletal disorder (MSD) risk, (b) to assess the relationship of force and repetition in fatigue failure studies of musculoskeletal tissues, and (c) to synthesize these findings.
backgroundMany epidemiological studies have examined the effects of force and repetition on MSD risk; however, relatively few have examined the interaction between these risk factors.
methodIn a literature search, we identified 12 studies that allowed evaluation of a force-repetition interaction with respect to MSD risk. Identified studies were subjected to a methodological quality assessment and critical review. We evaluated laboratory studies of fatigue failure to examine tissue failure responses to force and repetition.
resultsOf the 12 epidemiological studies that tested a Force x Repetition interaction, 10 reported evidence of interaction. Based on these results, the suggestion is made that force and repetition may be interdependent in terms of their influence on MSD risk. Fatigue failure studies of musculoskeletal tissues show a pattern of failure that mirrors the MSD risk observed in epidemiological studies.
conclusionsEvidence suggests that there may be interdependence between force and repetition with respect to MSD risk. Repetition seems to result in modest increases in risk for low-force tasks but rapid increases in risk for high-force tasks. This interaction may be representative of a fatigue failure process in affected tissues.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.