Trial reportPLoS neglected tropical diseases2013
Assessing the effect of an integrated control strategy for schistosomiasis japonica emphasizing bovines in a marshland area of Hubei Province, China: a cluster randomized trial.
Trial report in PLoS neglected tropical diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of the new integrated strategy to control the transmission of Schistosoma japonicum in China: a systematic review and meta-analysis.Parasite (Paris, France) · 2018Pooled it
- Identifying the Determinants of Distribution ofPathogens (Basel, Switzerland) · 2022Article
- Prevalence ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Comprehensive Risk Assessment of Schistosomiasis Epidemic Based on Precise Identification ofInternational journal of environmental research and public health · 2021Article
- The Stakeholders' Views on Planting Trees to Control Schistosomiasis in China.International journal of environmental research and public health · 2020Article
- Geographical Clustering and Environmental Determinants of Schistosomiasis from 2007 to 2012 in Jianghan Plain, China.International journal of environmental research and public health · 2018Article
- Animal influence on water, sanitation and hygiene measures for zoonosis control at the household level: A systematic literature review.PLoS neglected tropical diseases · 2018Review
- The Spatial-Temporal Trend Analysis of Schistosomiasis from 1997 to 2010 in Anhui Province, Eastern China.The American journal of tropical medicine and hygiene · 2018Article
- The role of ST2 and ST2 genetic variants in schistosomiasis.The Journal of allergy and clinical immunology · 2017Article
- Interruption of schistosomiasis transmission in mountainous and hilly regions with an integrated strategy: a longitudinal case study in Sichuan, China.Infectious diseases of poverty · 2017Article
- An integrated environmental improvement of marshlands: impact on control and elimination of schistosomiasis in marshland regions along the Yangtze River, China.Infectious diseases of poverty · 2017Article
- Approaches being used in the national schistosomiasis elimination programme in China: a review.Infectious diseases of poverty · 2017Review
- A multidisciplinary, integrated approach for the elimination of schistosomiasis: a longitudinal study in a historically hyper-endemic region in the lower reaches of the Yangtze River, China from 2005 to 2014.Infectious diseases of poverty · 2017Article
- Village-based spatio-temporal cluster analysis of the schistosomiasis risk in the Poyang Lake Region, China.Parasites & vectors · 2017Article
- Evaluation of protective efficacy induced by different heterologous prime-boost strategies encoding triosephosphate isomerase against Schistosoma japonicum in mice.Parasites & vectors · 2017Article
- Long-term effectiveness of the integrated schistosomiasis control strategy with emphasis on infectious source control in China: a 10-year evaluation from 2005 to 2014.Parasitology research · 2017Article
- Genetic diversity and structure of Schistosoma japonicum within two marshland villages of Anhui, China, prior to schistosome transmission control and elimination.Parasitology research · 2017Article
- Exposure to cows is not associated with diarrhoea or impaired child growth in rural Odisha, India: a cohort study.Epidemiology and infection · 2016Article
- Identifying Spatial Clusters of Schistosomiasis in Anhui Province of China: A Study from the Perspective of Application.International journal of environmental research and public health · 2015Article
- Spatial analysis of Schistosomiasis in Hubei Province, China: a GIS-based analysis of Schistosomiasis from 2009 to 2013.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMore than 80% of schistosomiasis patients in China live in the lake and marshland regions. The purpose of our study is to assess the effect of a comprehensive strategy to control transmission of Schistosoma japonicum in marshland regions. METHODOLOGY/PRINCIPAL
findingsIn a cluster randomized controlled trial, we implemented an integrated control strategy in twelve villages from 2009 through 2011 in Gong'an County, Hubei Province. The routine interventions included praziquantel chemotherapy and controlling snails, and were implemented in all villages. New interventions, mainly consisting of building fences to limit the grazing area for bovines, building safe pastures for grazing, improving the residents' health conditions and facilities, were only implemented in six intervention villages. Results showed that the rate of S. japonicum infection in humans, bovines, snails, cow dung and mice in the intervention group decreased from 3.41% in 2008 to 0.81% in 2011, 3.3% to none, 11 of 6,219 to none, 3.9% to none and 31.7% to 1.7%, respectively (P<0.001 for all comparisons). In contrast, there were no statistically significant reductions of S. japonicum infection in humans, bovines and snails from 2008 to 2011 in the control group (P>0.05 for all comparisons). Moreover, a generalized linear model showed that there was a higher infection risk in humans in the control group than in the intervention group (OR = 1.250, P = 0.001) and an overall significant downward trend in infection risk during the study period. CONCLUSIONS/SIGNIFICANCE: The integrated control strategy, designed to reduce the role of bovines and humans as sources of S. japonicum infection, was highly effective in controlling the transmission of S. japonicum in marshland regions in China.
trial registrationChinese Clinical Trial Registry ChiCTR-PRC-12002405.
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