Evidence map›Paper›PMID 23516645›Full record

ArticlePLoS neglected tropical diseases2013

Active surveillance of Hansen's Disease (leprosy): importance for case finding among extra-domiciliary contacts.

Maria L N Moura, Kathryn M Dupnik, Gabriel A A Sampaio, Priscilla F C Nóbrega, Ana K Jeronimo, Jose M do Nascimento-Filho, Roberta L Miranda Dantas, Jose W Queiroz, James D Barbosa, Gutemberg Dias and 3 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Review
  14. Leprosy surveillance study in a highly endemic Brazilian area using leprosy specific serologic tests and IFNγ whole blood assay.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maria L N MouraDepartment of Biochemistry, Biosciences Center, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Kathryn M Dupnik
Gabriel A A Sampaio
Priscilla F C Nóbrega
Ana K Jeronimo
Jose M do Nascimento-Filho
Roberta L Miranda Dantas
Jose W Queiroz
James D Barbosa
Gutemberg Dias
Selma M B Jeronimo
Marcia C F Souza
Maurício L Nobre

Funding

Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
FIC NIH HHS R25 TW009337
6 · The paper itself

Abstract

Hansen's disease (leprosy) remains an important health problem in Brazil, where 34,894 new cases were diagnosed in 2010, corresponding to 15.3% of the world's new cases detected in that year. The purpose of this study was to use home visits as a tool for surveillance of Hansen's disease in a hyperendemic area in Brazil. A total of 258 residences were visited with 719 individuals examined. Of these, 82 individuals had had a previous history of Hansen's disease, 209 were their household contacts and 428 lived in neighboring residences. Fifteen new Hansen's disease cases were confirmed, yielding a detection rate of 2.0% of people examined. There was no difference in the detection rate between household and neighbor contacts (p = 0.615). The two groups had the same background in relation to education (p = 0.510), household income (p = 0.582), and the number of people living in the residence (p = 0.188). Spatial analysis showed clustering of newly diagnosed cases and association with residential coordinates of previously diagnosed multibacillary cases. Active case finding is an important tool for Hansen's disease control in hyperendemic areas, enabling earlier diagnosis, treatment, decrease in disability from Hansen's disease and potentially less spread of Mycobacterium leprae.

Indexed as

Epidemiological MonitoringAdolescentAdultAgedAged, 80 and overBrazilChildChild, PreschoolCluster AnalysisContact TracingEndemic DiseasesFemaleHumansInfantInfant, NewbornLeprosy

Identifiers

PMID23516645
PMCPMC3597486

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.