ArticlePloS one2013
Personality, socio-economic status and inflammation: cross-sectional, population-based study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Five-factor model personality traits and inflammatory markers: new data and a meta-analysis.Psychoneuroendocrinology · 2014Pooled it
- Gastroesophageal reflux disease increases the risk of rheumatoid arthritis: a bidirectional two-sample Mendelian randomization study.Scientific reports · 2024Article
- Differentiating Stages of Bipolar and Unipolar Depression-The Possible Role of sICAM-1 and sVCAM-1.Cells · 2024Article
- Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis.Archives of medical science : AMS · 2024Article
- Rheumatoid arthritis and gastroesophageal reflux disease: a bidirectional and multivariable two-sample Mendelian randomization study.Frontiers in genetics · 2023Article
- Article
- Neuroticism is positively associated with leptin/adiponectin ratio, leptin and IL-6 in young adults.Scientific reports · 2021Article
- Bidirectional association between GERD and rheumatoid arthritis: two longitudinal follow-up studies using a national sample cohort.Clinical rheumatology · 2021Article
- JAK-Inhibitors for the Treatment of Rheumatoid Arthritis: A Focus on the Present and an Outlook on the Future.Biomolecules · 2020Review
- Personality and Incident Alzheimer's Disease: Theory, Evidence, and Future Directions.The journals of gerontology. Series B, Psychological sciences and social sciences · 2020Review
- Associations of Personality Traits With Chronic Low-Grade Inflammation in a Swiss Community Sample.Frontiers in psychiatry · 2019Article
- Roles of Heat Shock Proteins in Apoptosis, Oxidative Stress, Human Inflammatory Diseases, and Cancer.Pharmaceuticals (Basel, Switzerland) · 2017Review
- Socioeconomic Status Interacts with Conscientiousness and Neuroticism to Predict Circulating Concentrations of Inflammatory Markers.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2017Article
- Optimism, Cynical Hostility, Falls, and Fractures: The Women's Health Initiative Observational Study (WHI-OS).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Observational
- Personality and gene expression: Do individual differences exist in the leukocyte transcriptome?Psychoneuroendocrinology · 2015Article
- High interleukin-6 and impulsivity: determining the role of endophenotypes in attempted suicide.Translational psychiatry · 2014Article
- Infant SES as a predictor of personality--is the association mediated by intelligence?PloS one · 2014Article
- Impact of environmental factors on efficacy of glucocorticoids in Chinese population with systemic lupus erythematosus.Inflammation · 2013Article
- Oral Health and Risk of Arthritis in the Scottish Population: Results from the Scottish Health Survey.Journal of oral & maxillofacial researchArticle
- High Social Risk and Biomarkers of Systemic Inflammation: A Population-Based Study in Middle-Aged and Older Adults Living in Rural Communities.Journal of primary care & community healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 2 countries.
Funding
Abstract
backgroundAssociations between socio-economic status (SES), personality and inflammation were examined to determine whether low SES subjects scoring high on neuroticism or hostility might suffer relatively higher levels of inflammation than affluent subjects.
methodsIn a cross-sectional design, 666 subjects were recruited from areas of high (most deprived - "MD") and low (least deprived - "LD") deprivation. IL-6, ICAM-1, CRP and fibrinogen were measured along with demographic and health-behaviour variables, and personality traits of neuroticism, extraversion and psychoticism (hostility). Regression models assessed the prediction of inflammation as a function of personality, deprivation and their interaction.
resultsLevels of CRP and IL-6 were an increasing function of neuroticism and extraversion only in LD subjects opposite trends were seen in MD subjects. The result was ascribed parsimoniously to an inflammatory ceiling effect or, more speculatively, to SES-related health-behaviour differences. Psychoticism was strongly associated with ICAM-1 in both MD and LD subjects.
conclusionsThe association between neuroticism, CRP and IL-6 may be reduced in MD subjects confirming speculation that the association differs across population sub-groups. The association between psychoticism and ICAM-1 supports evidence that hostility has adverse effects upon the endothelium, with consequences for cardiovascular health. Health interventions may be more effective by accounting for personality-related effects upon biological processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.