Evidence map›Paper›PMID 23516427›Full record

ArticlePloS one2013

Transcriptome analysis of the role of GlnD/GlnBK in nitrogen stress adaptation by Sinorhizobium meliloti Rm1021.

Svetlana N Yurgel, Jennifer Rice, Michael L Kahn

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. TheFrontiers in microbiology · 2022
    Article
  2. Review
  3. Article
  4. Global Screening ofFrontiers in microbiology · 2017
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Svetlana N YurgelInstitute of Biological Chemistry, Washington State University, Pullman, Washington, USA. syurgel@wsu.edu
Jennifer Rice
Michael L Kahn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcriptional changes in the nitrogen stress response (NSR) of wild type S. meliloti Rm1021, and isogenic strains missing both PII proteins, GlnB and GlnK, or carrying a ΔglnD-sm2 mutation were analyzed using whole-genome microarrays. This approach allowed us to identify a number of new genes involved in the NSR and showed that the response of these bacteria to nitrogen stress overlaps with other stress responses, including induction of the fixK2 transcriptional activator and genes that are part of the phosphate stress response. Our data also show that GlnD and GlnBK proteins may regulate many genes that are not part of the NSR. Analysis of transcriptome profiles of the Rm1021 ΔglnD-sm2 strain allowed us to identify several genes that appear to be regulated by GlnD without the participation of the PII proteins.

Indexed as

Adaptation, BiologicalGene Expression ProfilingStress, PhysiologicalBacterial ProteinsGene Expression Regulation, BacterialModels, BiologicalMolecular Sequence AnnotationMutationNitrogenPhosphatesPII Nitrogen Regulatory ProteinsPolysaccharides, BacterialReproducibility of ResultsSinorhizobium melilotiBacterial ProteinsNitrogenPhosphatesPII Nitrogen Regulatory ProteinsPolysaccharides, Bacterialsuccinoglycan

Identifiers

PMID23516427
PMCPMC3596328

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.