Evidence map›Paper›PMID 23516142›Full record

ReviewNeuroscience bulletin2013

Polydendrocytes in development and myelin repair.

Hao Zuo, Akiko Nishiyama

Abstract readReview
In one paragraph

Review in Neuroscience bulletin, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. GlialNeural regeneration research · 2017
    Review
  8. Article
  9. Article
  10. Living scaffolds for neuroregeneration.Current opinion in solid state & materials science · 2014
    Article
  11. Neuroscience. To learn is to myelinate.Science (New York, N.Y.) · 2014
    Article
  12. Review
  13. Review
  14. Review
  15. Myelin in development and disease.Neuroscience bulletin · 2013
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hao ZuoDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269-3156, USA.
Akiko Nishiyama

Funding

Inflammation and NG2 Cell DifferentiationR01NS073425 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2011 to 2021
$3.3M
Heterogeneity of NG2 Glial CellsR01NS074870 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2012 to 2016
$1.7M
Regulation of glial lineage by Olig2R21NS069960 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO, WRIGHT, DENNIS L. · 2010 to 2011
$402k
NINDS NIH HHS R01 NS073425NINDS NIH HHS R01 NS074870NINDS NIH HHS R21 NS069960
6 · The paper itself

Abstract

Polydendrocytes (NG2 cells) are a distinct type of glia that populate the developing and adult central nervous systems (CNS). In the adult CNS, they retain mitotic activity and represent the largest proliferating cell population. Genetic and epigenetic mechanisms regulate the fate of polydendrocytes, which give rise to both oligodendrocytes and astrocytes. In addition, polydendrocytes actively differentiate into myelin-forming oligodendrocytes in response to demyelination. This review summarizes the current knowledge regarding polydendrocyte development, which provides an important basis for understanding the mechanisms that lead to the remyelination of demyelinated lesions.

Indexed as

AnimalsAntigensCell DifferentiationCentral Nervous SystemChondroitin Sulfate Proteoglycan 4HumansMyelin SheathNerve RegenerationOligodendrogliaProteoglycansSignal TransductionAntigensChondroitin Sulfate Proteoglycan 4Proteoglycans

Identifiers

PMID23516142
PMCPMC3959157

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.