Evidence map›Paper›PMID 23516077›Full record

ArticleMedical & biological engineering & computing2013

Modelling physiological deterioration in post-operative patient vital-sign data.

Marco A F Pimentel, David A Clifton, Lei Clifton, Peter J Watkinson, Lionel Tarassenko

Abstract read
In one paragraph

Article in Medical & biological engineering & computing, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco A F PimentelInstitute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Old Road Campus Research Building (Off Roosevelt Drive), Oxford OX3 7DQ, UK. marco.pimentel@eng.ox.ac.uk
David A Clifton
Lei Clifton
Peter J Watkinson
Lionel Tarassenko

Funding

Wellcome TrustWellcome Trust WT 088877/Z/09/Z
6 · The paper itself

Abstract

Patients who undergo upper-gastrointestinal surgery have a high incidence of post-operative complications, often requiring admission to the intensive care unit several days after surgery. A dataset comprising observational vital-sign data from 171 post-operative patients taking part in a two-phase clinical trial at the Oxford Cancer Centre, was used to explore the trajectory of patients' vital-sign changes during their stay in the post-operative ward using both univariate and multivariate analyses. A model of normality based vital-sign data from patients who had a "normal" recovery was constructed using a kernel density estimate, and tested with "abnormal" data from patients who deteriorated sufficiently to be re-admitted to the intensive care unit. The vital-sign distributions from "normal" patients were found to vary over time from admission to the post-operative ward to their discharge home, but no significant changes in their distributions were observed from halfway through their stay on the ward to the time of discharge. The model of normality identified patient deterioration when tested with unseen "abnormal" data, suggesting that such techniques may be used to provide early warning of adverse physiological events.

Indexed as

Models, BiologicalPostoperative PeriodSignal Processing, Computer-AssistedAgedAlgorithmsAnalysis of VarianceDatabases, FactualDigestive System Surgical ProceduresFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedModels, StatisticalVital Signs

Identifiers

PMID23516077
PMCPMC3709086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.