Evidence map›Paper›PMID 23515863›Full record

ArticleJournal of biomedical optics2013

Imaging and quantifying Brownian motion of micro- and nanoparticles using phase-resolved Doppler variance optical coherence tomography.

Chang Soo Kim, Wenjuan Qi, Jun Zhang, Young Jik Kwon, Zhongping Chen

Abstract readLetter
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Probing biological nanotopology via diffusion of weakly constrained plasmonic nanorods with optical coherence tomography.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chang Soo Kim
Wenjuan Qi
Jun Zhang
Young Jik Kwon
Zhongping Chen

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY · 2012 to 2017
$7.0M
Modeling the Pediatric Upper Airway using A-OCT and Computational Fluid DynamicsR01HL105215 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ELGHOBASHI, SAID E. · 2010 to 2013
$3.7M
Diagnosis of Subglottic Stenosis and Edema in Neonates Using OCTR01HL103764 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI WONG, BRIAN · 2010 to 2014
$3.1M
Integrated multi-modality intravascular US/OCT imaging systemR01EB010090 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING · 2009 to 2012
$2.3M
Elastographic Imaging of the Retina/Choroid in Age-Related Macular DegenerationR01EY021529 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHEN, ZHONGPING, SILVERMAN, RONALD H · 2012 to 2015
$1.4M
Mechanisms of lens growth regulationR01EY021519 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI GONG, XIAOHUA · 2011 to 2014
$1.2M
Evaluation of obstructive sleep apnea with long range 3D endoscopic FDOCTK25HL102055 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI ZHANG, JUN · 2011 to 2014
$495k
NEI NIH HHS R01 EY-021519NEI NIH HHS R01 EY021519NEI NIH HHS R01 EY021529NHLBI NIH HHS K25 HL-102055NHLBI NIH HHS K25 HL102055NHLBI NIH HHS R01 HL-103764NHLBI NIH HHS R01 HL103764NHLBI NIH HHS R01 HL-105215NHLBI NIH HHS R01 HL105215NIBIB NIH HHS P41 EB-015890NIBIB NIH HHS P41 EB015890NIBIB NIH HHS R01 EB010090NIBIB NIH HHS R01 EB-10090
6 · The paper itself

Abstract

Different types and sizes of micro- and nanoparticles have been synthesized and developed for numerous applications. It is crucial to characterize the particle sizes. Traditional dynamic light scattering, a predominant method used to characterize particle size, is unable to provide depth resolved information or imaging functions. Doppler variance optical coherence tomography (OCT) measures the spectral bandwidth of the Doppler frequency shift due to the Brownian motion of the particles utilizing the phase-resolved approach and can provide quantitative information about particle size. Spectral bandwidths of Doppler frequency shifts for various sized particles were quantified and were demonstrated to be inversely proportional to the diameter of the particles. The study demonstrates the phase-resolved Doppler variance spectral domain OCT technique has the potential to be used to investigate the properties of particles in highly scattering media.

Indexed as

Doppler EffectFourier AnalysisGoldMetal NanoparticlesMicrospheresPhysical PhenomenaPolystyrenesTomography, Optical CoherenceGoldPolystyrenes

Identifiers

PMID23515863
PMCPMC3603150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.