Evidence map›Paper›PMID 23515852›Full record

ArticleEnvironmental health insights2013

Atrazine and nitrate in public drinking water supplies and non-hodgkin lymphoma in nebraska, USA.

Martha G Rhoades, Jane L Meza, Cheryl L Beseler, Patrick J Shea, Andy Kahle, Julie M Vose, Kent M Eskridge, Roy F Spalding

Open access · goldAbstract read
In one paragraph

Article in Environmental health insights, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Martha G RhoadesSchool of Natural Resources, University of Nebraska-Lincoln, Lincoln, Nebraska.
Jane L Meza
Cheryl L Beseler
Patrick J Shea
Andy Kahle
Julie M Vose
Kent M Eskridge
Roy F Spalding
University of Nebraska–Lincoln · USUniversity of Nebraska Medical Center · USColorado State University · USNebraska Department of Health and Human Services · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A secondary analysis of 1999-2002 Nebraska case-control data was conducted to assess the risk of non-Hodgkin lymphoma (NHL) associated with exposure to nitrate- and atrazine-contaminated drinking water. Water chemistry data were collected and weighted by well contribution and proximity of residence to water supply, followed by logistic regression to determine odds ratios (OR) and 95% confidence intervals (CI). We found no association between NHL risk and exposure to drinking water containing atrazine or nitrate alone. Risk associated with the interaction of nitrate and atrazine in drinking water was elevated (OR, 2.5; CI, 1.0-6.2). Risk of indolent B-cell lymphoma was higher than risk of aggressive B-cell lymphoma (indolent: OR, 3.5; CI, 1.0-11.6 vs. aggressive: OR, 1.9; CI, 0.6-5.58). This increased risk may be due to in vivo formation and subsequent metabolism of N-nitrosoatrazine. A larger study is warranted to confirm our findings.

Indexed as

atrazinedrinking waterNHLnitratenitrosamines

Identifiers

PMID23515852
PMCPMC3595994
OpenAlexW2072353549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.