ReviewAmerican journal of physiology. Renal physiology2013
Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity.
Review in American journal of physiology. Renal physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Molecular Mechanisms of Sepsis-Associated Acute Kidney Injury.Journal of the American Society of Nephrology : JASN · 2025Review
- Intravital Multiphoton Microscopy as a Tool for Studying Renal Physiology, Pathophysiology and Therapeutics.Frontiers in physiology · 2022Review
- Tissue Cytometry With Machine Learning in Kidney: From Small Specimens to Big Data.Frontiers in physiology · 2022Review
- Renal cystic disease in tuberous sclerosis complex.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Zhen-Wu-Tang Protects IgA Nephropathy in Rats by Regulating Exosomes to Inhibit NF-κB/NLRP3 Pathway.Frontiers in pharmacology · 2020Article
- Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Review
- Immune mechanisms in the different phases of acute tubular necrosis.Kidney research and clinical practice · 2018Review
- Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection.JCI insight · 2018Article
- Autoinflammatory disease in the lung.Immunology · 2018Review
- Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.Journal of the American Society of Nephrology : JASN · 2018Article
- Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney.Journal of the American Society of Nephrology : JASN · 2018Article
- Two-Photon Intravital Fluorescence Lifetime Imaging of the Kidney Reveals Cell-Type Specific Metabolic Signatures.Journal of the American Society of Nephrology : JASN · 2017Article
- Molecular differences in susceptibility of the kidney to sepsis-induced kidney injury.BMC nephrology · 2017Article
- A brief journey through the immune system.Clinical journal of the American Society of Nephrology : CJASN · 2015Review
- Tubular cross talk in acute kidney injury: a story of sense and sensibility.American journal of physiology. Renal physiology · 2015Review
- Therapeutic translation in acute kidney injury: the epithelial/endothelial axis.The Journal of clinical investigation · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The importance of innate immunity for survival is underscored by its presence at almost every level of the evolutionary tree of life. The task of "danger" recognition by the innate immune system is carried out by a broad class of pattern recognition receptors. These receptors are expressed in both hematopoietic and nonhematopoietic cells such as renal epithelial cells. Upon activation, pattern recognition receptors induce essentially two types of defensive responses: inflammation and phagocytosis. In this review, we highlight evidence that renal epithelial cells are endowed with such defensive capabilities and as such fully participate in renal innate immune responses.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.