ArticleCurrent pathobiology reports2013
MicroRNA and Epigenetics: Diagnostic and Therapeutic Opportunities.
Article in Current pathobiology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- MicroRNAs, small regulatory elements with significant effects on human implantation: a review.Journal of assisted reproduction and genetics · 2023Review
- The Epigenetic Landscape of Meningiomas.Advances in experimental medicine and biology · 2023Article
- The New Face of a Well-Known Antibiotic: A Review of the Anticancer Activity of Enoxacin and Its Derivatives.Cancers · 2022Review
- Identification of Novel miRNAs in the F8 Gene Via Bioinformatics Tools.Iranian journal of biotechnology · 2021Article
- Overview of host miRNA properties and their association with epigenetics, long non-coding RNAs, and Xeno-infectious factors.Cell & bioscience · 2021Review
- Modulating microRNA Processing: Enoxacin, the Progenitor of a New Class of Drugs.Journal of medicinal chemistry · 2020Article
- The MicroRNA Family Both in Normal Development and in Different Diseases: The miR-17-92 Cluster.BioMed research international · 2019Review
- Prediction of Potential Small Molecule-Associated MicroRNAs Using Graphlet Interaction.Frontiers in pharmacology · 2018Article
- Mosaicism in Cutaneous Disorders.Annual review of genetics · 2017Review
- miR-219-5p targets CaMKIIγ to attenuate morphine tolerance in rats.Oncotarget · 2017Article
- Downregulation of miR-33a-5p in Hepatocellular Carcinoma: A Possible Mechanism for Chemotherapy Resistance.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Molecular basis of chronic lymphocytic leukemia diagnosis and prognosis.Cellular oncology (Dordrecht, Netherlands) · 2015Review
- MicroRNAs in cancer therapeutics: "from the bench to the bedside".Expert opinion on biological therapy · 2015Article
- Epigenetics of Meningiomas.BioMed research international · 2015Review
- Small molecule compounds targeting miRNAs for cancer therapy.Advanced drug delivery reviews · 2015Review
- Lost miRNA surveillance of Notch, IGFR pathway--road to sarcomagenesis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- MicroRNAs as pharmacological targets in diabetes.Pharmacological research · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression that control cellular and developmental processes by targeting messenger RNAs (mRNA). These small non-coding RNAs (ncRNAs) are aberrantly expressed in cancer, and are known to contribute to tumorigenesis and disease progression. Therapeutic strategies based on modulating miRNAs activity are emerging due to the ability of these ncRNAs to influence cellular behavior. MiRNA levels predict disease prognosis and overall patient survival, and reconstituting their basal levels has been proven to inhibit tumor growth and metastasis. Different delivery mechanisms have been tested
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.