Evidence map›Paper›PMID 23515373›Full record

Trial reportFamily practice2013

Value associated with mindfulness meditation and moderate exercise intervention in acute respiratory infection: the MEPARI Study.

David Rakel, Marlon Mundt, Tola Ewers, Luke Fortney, Aleksandra Zgierska, Michele Gassman, Bruce Barrett

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Family practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01057771 (Meditation and Exercise for Prevention of Acute Respiratory Infection), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01057771 phase2 / phase3completednot on this map

Meditation and Exercise for Prevention of Acute Respiratory Infection

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2009 to 2010Enrolled154ConditionsAcute Respiratory InfectionArmsMeditation, Exercise
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Improved Health and Well-being: Creating Value in Health Care.Integrative medicine (Encinitas, Calif.) · 2017
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David RakelDepartment of Family Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715, USA. drakel@uwhealth.org
Marlon Mundt
Tola Ewers
Luke Fortney
Aleksandra Zgierska
Michele Gassman
Bruce Barrett
University of Wisconsin–Madison · USUniversity of Wisconsin Health · US

Funding

Meditation and Exercise for Prevention of Acute Respiratory InfectionR01AT004313 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2009 to 2010
$1.2M
Mentoring and research in patient-oriented medicineK24AT006543 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2012 to 2016
$818k
NCCIH NIH HHS K24 AT006543NCCIH NIH HHS R01 AT004313
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAcute respiratory infection (ARI) is among the most common, debilitating and expensive human illnesses. The purpose of this study was to assess ARI-related costs and determine if mindfulness meditation or exercise can add value.

methodsOne hundred and fifty-four adults ≥50 years from Madison, WI for the 2009-10 cold/flu season were randomized to (i) wait-list control (ii) meditation or (iii) moderate intensity exercise. ARI-related costs were assessed through self-reported medication use, number of missed work days and medical visits. Costs per subject were based on cost of generic medications, missed work days ($126.20) and clinic visits ($78.70). Monte Carlo bootstrap methods evaluated reduced costs of ARI episodes.

resultsThe total cost per subject for the control group was $214 (95% CI: $105-$358), exercise $136 (95% CI: $64-$232) and meditation $65 (95% CI: $34-$104). The majority of cost savings was through a reduction in missed days of work. Exercise had the highest medication costs at $16.60 compared with $5.90 for meditation (P = 0.004) and $7.20 for control (P = 0.046). Combining these cost benefits with the improved outcomes in incidence, duration and severity seen with the Meditation or Exercise for Preventing Acute Respiratory Infection study, meditation and exercise add value for ARI. Compared with control, meditation had the greatest cost benefit. This savings is offset by the cost of the intervention ($450/subject) that would negate the short-term but perhaps not long-term savings.

conclusionsMeditation and exercise add value to ARI-associated health-related costs with improved outcomes. Further research is needed to confirm results and inform policies on adding value to medical spending.

Indexed as

Cost of IllnessExercise TherapyMeditationMindfulnessRespiratory Tract InfectionsAcute DiseaseAmbulatory CareCosts and Cost AnalysisHumansMaleMedication AdherenceMiddle AgedOutcome Assessment, Health CareSick LeaveTreatment OutcomeWaiting ListsComplementary and alternative medicinehealth economicsphysical activity/exercisepreventionupper respiratory infection/common coldvalue.

Identifiers

PMID23515373
PMCPMC3722506
OpenAlexW2150822918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.