ArticleNature2013
CLASP-mediated cortical microtubule organization guides PIN polarization axis.
Article in Nature, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Phosphorylation of ADAPTOR PROTEIN-2 μ-adaptin by ADAPTOR-ASSOCIATED KINASE1 regulates the tropic growth of Arabidopsis roots.The Plant cell · 2023Article
- Promoter Variation of the Key Apple Fruit Texture Related GenePlants (Basel, Switzerland) · 2023Article
- Long Non-Coding RNAs as Emerging Regulators of Pathogen Response in Plants.Non-coding RNA · 2022Review
- Genome-wide identification and characterization of the CLASP_N gene family in upland cotton (PeerJ · 2022Article
- Identification and Functional Characterization of a Microtubule-Associated Protein, GhCLASP2, From Upland Cotton (Frontiers in plant science · 2018Article
- Long non-coding RNAs and their biological roles in plants.Genomics, proteomics & bioinformatics · 2015Review
- The far side of auxin signaling: fundamental cellular activities and their contribution to a defined growth response in plants.Protoplasma · 2014Article
- Retraction: CLASP-mediated cortical microtubule organization guides PIN polarization axis.Nature · 2014Article
- Cellulose synthesis and its regulation.The arabidopsis book · 2014Article
- Interactions between auxin, microtubules and XTHs mediate green shade- induced petiole elongation in arabidopsis.PloS one · 2014Article
- Phototropism: growing towards an understanding of plant movement.The Plant cell · 2014Article
- Arabidopsis AUGMIN subunit8 is a microtubule plus-end binding protein that promotes microtubule reorientation in hypocotyls.The Plant cell · 2013Article
- Inactivation of plasma membrane-localized CDPK-RELATED KINASE5 decelerates PIN2 exocytosis and root gravitropic response in Arabidopsis.The Plant cell · 2013Article
- Arabidopsis SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity.Nature communications · 2013Article
Corrections and comments
- Retraction · 2014-03-19Duplication of/in Image · Error in Image · Manipulation of Images ·
- Retracted
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent evidence indicates a correlation between orientation of the plant cortical microtubule cytoskeleton and localization of polar cargoes. However, the molecules and mechanisms that create this correlation have remained unknown. Here we show that, in Arabidopsis thaliana, the microtubule orientation regulators CLASP and MAP65 (refs 3, 4) control the abundance of polarity regulator PINOID kinase at the plasma membrane. By localized upregulation of clathrin-dependent endocytosis at cortical microtubule- and clathrin-rich domains orthogonal to the axis of polarity, PINOID accelerates the removal of auxin transporter PIN proteins from those sites. This mechanism links directional microtubule organization to the polar localization of auxin transporter PIN proteins, and clarifies how microtubule-enriched cell sides are kept distinct from polar delivery domains. Our results identify the molecular machinery that connects microtubule organization to the regulation of the axis of PIN polarization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.