ArticleKidney international2013
Interdialytic weight gain, systolic blood pressure, serum albumin, and C-reactive protein levels change in chronic dialysis patients prior to death.
Article in Kidney international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 60 citations in OpenAlex.
- Biphasic Dynamics of Inflammatory Markers Following Hemodialysis Initiation: Results From the International MONitoring Dialysis Outcome Initiative.Kidney international reports · 2023Article
- Ultrafiltration Rate Thresholds Associated With Increased Mortality Risk in Hemodialysis, Unscaled or Scaled to Body Size.Kidney international reports · 2022Article
- Prediction models for mortality risk in patients initiating dialysis. Are they ready?Journal of nephrology · 2022Article
- Article
- Relationship between serum phosphate levels and survival in chronic hemodialysis patients: interactions with age, malnutrition and inflammation.Clinical kidney journal · 2021Article
- Clinical and predictive value of simplified creatinine index used as muscle mass surrogate in end-stage kidney disease haemodialysis patients-results from the international MONitoring Dialysis Outcome initiative.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- Wearable health devices and personal area networks: can they improve outcomes in haemodialysis patients?Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Review
- Using Bioimpedance Spectroscopy to Assess Volume Status in Dialysis Patients.Blood purification · 2020Review
- Non-adherence to Haemodialysis, Interdialytic weight gain and cardiovascular mortality: a cohort study.BMC nephrology · 2019Article
- Cycles, Arrows and Turbulence: Time Patterns in Renal Disease, a Path from Epidemiology to Personalized Medicine?Blood purification · 2019Review
- Article
- Greater fluid overload and lower interdialytic weight gain are independently associated with mortality in a large international hemodialysis population.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2018Article
- Association of Kidney Disease Quality of Life (KDQOL-36) with mortality and hospitalization in older adults receiving hemodialysis.BMC nephrology · 2018Article
- Joint modeling of longitudinal, recurrent events and failure time data for survivor's population.Biometrics · 2017Article
- Analysis of Factors Associated with Death in Maintenance Hemodialysis Patients: A Multicenter Study in China.Chinese medical journal · 2017Article
- Aging and death-associated changes in serum albumin variability over the course of chronic hemodialysis treatment.PloS one · 2017Article
- Semiparametric modeling and estimation of the terminal behavior of recurrent marker processes before failure events.Journal of the American Statistical Association · 2017Article
- Nutritional Competence and Resilience among Hemodialysis Patients in the Setting of Dialysis Initiation and Hospitalization.Clinical journal of the American Society of Nephrology : CJASN · 2015Article
- Seasonal variations in mortality and clinical indicators in international hemodialysis populations from the MONDO registry.BMC nephrology · 2015Article
- Development and validation of a predictive mortality risk score from a European hemodialysis cohort.Kidney international · 2015Article
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Authors and funding
20 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reports from a United States cohort of chronic hemodialysis patients suggested that weight loss, a decline in pre-dialysis systolic blood pressure, and decreased serum albumin may precede death. However, no comparative studies have been reported in such patients from other countries. Here we analyzed dynamic changes in these parameters in hemodialysis patients and included 3593 individuals from 5 Asian countries; 35,146 from 18 European countries; 8649 from Argentina; and 4742 from the United States. In surviving prevalent patients, these variables appeared to have notably different dynamics than in patients who died. While in all populations the interdialytic weight gain, systolic blood pressure, and serum albumin levels were stable in surviving patients, these indicators declined starting more than a year ahead in those who died with the dynamics similar irrespective of gender and geographic region. In European patients, C-reactive protein levels were available on a routine basis and indicated that levels of this acute-phase protein were low and stable in surviving patients but rose sharply before death. Thus, relevant fundamental biological processes start many months before death in the majority of chronic hemodialysis patients. Longitudinal monitoring of these dynamics may help to identify patients at risk and aid the development of an alert system to initiate timely interventions to improve outcomes.
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