Evidence map›Paper›PMID 23514672›Full record

ArticleThe American journal of the medical sciences2014

Association between metabolic syndrome and its individual components with viral hepatitis B.

Raxitkumar Jinjuvadia, Suthat Liangpunsakul

Abstract read
In one paragraph

Article in The American journal of the medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Paradox of hepatitis B: Metabolic risk and cardiovascular protection in a national cohort.International journal of cardiology. Cardiovascular risk and prevention · 2026
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  5. Review
  6. Article
  7. Article
  8. Association between chronic hepatitis B infection and metabolic syndrome.Journal of diabetes and metabolic disorders · 2018
    Article
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  10. Article
  11. [Clinical research advances in chronic hepatitis B complicated by fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2018
    Article
  12. Article
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  14. Observational
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  17. Review
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Raxitkumar JinjuvadiaDepartment of Internal Medicine (RJ), Detroit Medical Center, Detroit, Michigan; Division of Gastroenterology and Hepatology (SL), Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana; and Roudebush Veterans Administration Medical Center (SL), Indianapolis, Indiana.
Suthat Liangpunsakul
Detroit Medical Center · USUniversity Hospital and Clinics · US

Funding

Effect of ethanol on Kupffer cell/hepatocyte interactions and lipid metabolismK08AA016570 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI LIANGPUNSAKUL, SUTHAT · 2008 to 2012
$659k
CSRD VA I01 CX000361NIAAA NIH HHS K08 AA016570
6 · The paper itself

Abstract

backgroundThe association between hepatitis B and metabolic syndrome (MetS) has not been well described. Overall epidemiologic evidences for this association have suggested conflicting results. The aim this study was to determine the association between hepatitis B infection and MetS using large U.S. population database, the Third National Health and Nutrition Examination Survey.

methodsIndividuals aged ≥18 years were included in this study. MetS was defined according to the Third Report of the National Cholesterol Education Program Adult Treatment Panel guideline. The chronic hepatitis B was defined as the presence of hepatitis B surface antigen. The presence of hepatitis B core antibody with/without surface antibody, in the absence of surface antigen, was considered as past exposure to hepatitis B. To represent national estimates, weighted frequencies for chronic hepatitis B and past exposure to hepatitis B are reported. Multivariate logistic regression analysis accounting for age, gender, race, smoking and alcohol status was conducted to identify the independent predictor(s) of MetS.

resultsThis study cohort consisted of total population of 593,594 with chronic hepatitis B and 7,280,620 with past exposure to hepatitis B. Prevalence of MetS among included study cohort was 25.7%. Inverse association was observed between MetS and chronic hepatitis B (adjusted odds ratio, 0.32; 95% confidence interval, 0.12-0.84). Among individual components of MetS, waist circumference was inversely associated with chronic hepatitis B (adjusted odds ratio, 0.31; 95% confidence interval, 0.14-0.71). No significant association was noted between past exposure to hepatitis B and MetS or its individual components.

conclusionsIn this study, the authors noted significant inverse association between MetS and chronic hepatitis B.

Indexed as

Waist CircumferenceAdultBlood GlucoseCase-Control StudiesCholesterol, HDLCohort StudiesFemaleHepatitis B AntibodiesHepatitis B AntigensHepatitis B, ChronicHumansLogistic ModelsMaleMetabolic SyndromeMiddle AgedNutrition SurveysBlood GlucoseCholesterol, HDLHepatitis B AntibodiesHepatitis B Antigens

Identifiers

PMID23514672
PMCPMC3723745
OpenAlexW2014043599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.