Evidence map›Paper›PMID 23514142›Full record

ReviewBiochemical Society transactions2013

Insights into chromatin fibre structure by in vitro and in silico single-molecule stretching experiments.

Rosana Collepardo-Guevara, Tamar Schlick

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. The chromatin fiber: multiscale problems and approaches.Current opinion in structural biology · 2015
    Review
  7. Forced unraveling of chromatin fibers with nonuniform linker DNA lengths.Journal of physics. Condensed matter : an Institute of Physics journal · 2015
    Article
  8. Article
  9. Chromatin fiber polymorphism triggered by variations of DNA linker lengths.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rosana Collepardo-GuevaraDepartment of Chemistry, New York University, 100 Washington Square East, New York, NY 10003, U.S.A.
Tamar Schlick

Funding

Modeling Chromatin Organization and FunctionR01GM055164 · NIGMS · NEW YORK UNIVERSITY · PI SCHLICK, TAMAR · 1998 to 2015
$2.6M
NIGMS NIH HHS R01 GM055164NIGMS NIH HHS R01 GM55164
6 · The paper itself

Abstract

The detailed structure and dynamics of the chromatin fibre and their relation to gene regulation represent important open biological questions. Recent advances in single-molecule force spectroscopy experiments have addressed these questions by directly measuring the forces that stabilize and alter the folded states of chromatin, and by investigating the mechanisms of fibre unfolding. We present examples that demonstrate how complementary modelling approaches have helped not only to interpret the experimental findings, but also to advance our knowledge of force-induced events such as unfolding of chromatin with dynamically bound linker histones and nucleosome unwrapping.

Indexed as

Computer SimulationBiomechanical PhenomenaChromatinHistonesSpectrum AnalysisChromatinHistones

Identifiers

PMID23514142
PMCPMC3683968

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.