ArticleObesity (Silver Spring, Md.)2013
Metabolic consequences of the early onset of obesity in common marmoset monkeys.
Article in Obesity (Silver Spring, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Predictive markers of obesity and glucose metabolism dysfunction in adult common marmosets (Callithrix jacchus).International journal of obesity (2005) · 2025Article
- Association of Primate Veterinarians Guidelines for Weight Management in Research Nonhuman Primates.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Validation of Body Condition Scoring as a Screening Test for Low Body Condition and Obesity in Common Marmosets (Callithrix jacchus).American journal of primatology · 2025Article
- Article
- Review of Environmental and Health Factors Impacting Captive Common Marmoset Welfare in the Biomedical Research Setting.Veterinary sciences · 2023Review
- Development and validation of an LC-MS/MS based quantitative assay for marmoset insulin in serum.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2022Article
- Current practices in nutrition management and disease incidence of common marmosets (Callithrix jacchus).Journal of medical primatology · 2021Article
- Protective effects of the imidazoline-like drug lnp599 in a marmoset model of obesity-induced metabolic disorders.International journal of obesity (2005) · 2021Article
- Marmoset Metabolism, Nutrition, and Obesity.ILAR journal · 2020Review
- Marmosets: Welfare, Ethical Use, and IACUC/Regulatory Considerations.ILAR journal · 2020Review
- Clinical Management of Gastrointestinal Disease in the Common Marmoset (Callithrix jacchus).ILAR journal · 2020Review
- Feasibility of fecal microbiota transplantation via oral gavage to safely alter gut microbiome composition in marmosets.American journal of primatology · 2020Article
- Generation of genetically engineered non-human primate models of brain function and neurological disorders.American journal of primatology · 2019Review
- Maternal High-Fat Diet Effects on Adaptations to Metabolic Challenges in Male and Female Juvenile Nonhuman Primates.Obesity (Silver Spring, Md.) · 2018Article
- The common marmoset monkey: avenues for exploring the prenatal, placental, and postnatal mechanisms in developmental programming of pediatric obesity.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Review
- Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus).PloS one · 2017Article
- Neurobehavioral development of common marmoset monkeys.Developmental psychobiology · 2016Review
- Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus).Aging · 2015Article
- Relation of food intake behaviors and obesity development in young common marmoset monkeys.Obesity (Silver Spring, Md.) · 2013Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveThe common marmoset as a model of early obesity was assessed. The hypotheses that juvenile marmosets with excess adipose tissue will display higher fasting glucose, decreased insulin sensitivity, and decreased ability to clear glucose from the blood stream were tested. DESIGN AND
methodsNormal and obese (body fat > 14%) common marmoset infants (N = 39) were followed up from birth until 1 year. Body fat was measured by quantitative magnetic resonance. Circulating glucose was measured by glucometer and insulin, adiponectin, and leptin by commercial assays. The quantitative insulin sensitivity check index (QUICKI; a measure of insulin sensitivity) was calculated for subjects with fasting glucose and insulin measures. Oral glucose tolerance tests (OGTTs) were conducted at 12 months on 35 subjects.
resultsAt 6 months, obese subjects already had significantly lower insulin sensitivity (mean QUICKI = 0.378 ± 0.029 vs. 0.525 ± 0.019, N = 11, P = 0.003). By 12 months, obese subjects also had higher fasting glucose (129.3 ± 9.1 mg/dL vs. 106.1 ± 6.5 mg/dL, P = 0.042), and circulating adiponectin tended to be lower (P = 0.057). Leptin was associated with percent body fat; however, birth weight also influenced circulating leptin. The OGTT results demonstrated that obese animals had a decreased ability to clear glucose.
conclusionsEarly-onset obesity in marmosets results in impaired glucose homeostasis by 1 year.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.