Evidence map›Paper›PMID 23512841›Full record

ReviewObesity (Silver Spring, Md.)2013

Gastrointestinal hormones and bariatric surgery-induced weight loss.

Viorica Ionut, Miguel Burch, Adrienne Youdim, Richard N Bergman

Open access · bronzeAbstract readReview
In one paragraph

Review in Obesity (Silver Spring, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 156 citations in OpenAlex.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Viorica IonutDiabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA. Viorica.Ionut@cshs.org
Miguel Burch
Adrienne Youdim
Richard N Bergman
Cedars-Sinai Medical Center · US

Funding

QUANTITATION OF FACTORS REGULATING GLUCOSE TOLERANCER01DK029867 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MARILYN ADER · 1986 to 2026
$11.0M
Quantitative Studies of Metabolic Organ DynamicsR37DK027619 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERGMAN, RICHARD NATHAN · 2007 to 2016
$6.2M
NIDDK NIH HHS R01 DK029867NIDDK NIH HHS R01 DK 29867NIDDK NIH HHS R37 DK027619NIDDK NIH HHS R37 DK 27619
6 · The paper itself

Abstract

unlabelledObesity continues to be a major public health problem in the United States and worldwide. While recent statistics have demonstrated that obesity rates have begun to plateau, more severe classes of obesity are accelerating at a faster pace with important implications in regards to treatment. Bariatric surgery has a profound and durable effect on weight loss, being to date one of the most successful interventions for obesity.

objectiveTo provide updates to the possible role of gut hormones in post bariatric surgery weight loss and weight loss maintenance. DESIGN AND

methodsThe current review examines the changes in gastro-intestinal hormones with bariatric surgery and the potential mechanisms by which these changes could result in decreased weight and adiposity.

resultsThe mechanism by which bariatric surgery results in body weight changes is incompletely elucidated, but it clearly goes beyond caloric restriction and malabsorption.

conclusionChanges in gastro-intestinal hormones, including increases in GLP-1, PYY, and oxyntomodulin, decreases in GIP and ghrelin, or the combined action of all these hormones might play a role in induction and long-term maintenance of weight loss.

Indexed as

Bariatric SurgeryWeight LossBile Acids and SaltsCaloric RestrictionDiabetes Mellitus, Type 2Gastrointestinal HormonesGhrelinGlucagon-Like Peptide 1HumansObesityOxyntomodulinPeptide YYPostoperative PeriodUnited StatesBile Acids and SaltsGastrointestinal HormonesGhrelinGlucagon-Like Peptide 1OxyntomodulinPeptide YY

Identifiers

PMID23512841
PMCPMC4423817
OpenAlexW1520944897

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.