Evidence map›Paper›PMID 23512321›Full record

ArticleAmerican journal of perinatology2014

Perinatal outcomes of multiple-gestation pregnancies in Kenya, Zambia, Pakistan, India, Guatemala, and Argentina: a global network study.

Irene Marete, Constance Tenge, Omrana Pasha, Shivaprasad Goudar, Elwyn Chomba, Archana Patel, Fernando Althabe, Ana Garces, Elizabeth M McClure, Sarah Saleem and 14 more

Open access · greenAbstract read
In one paragraph

Article in American journal of perinatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Predictors and outcomes of low birth weight in Lusaka, Zambia.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2016
    Article
  11. Review
  12. Observational
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 17 institutions in 8 countries.

Irene MareteDepartment of Child Health and Paediatrics, Moi University School of Medicine, Eldoret, Kenya.
Constance TengeDepartment of Child Health and Paediatrics, Moi University School of Medicine, Eldoret, Kenya.
Omrana PashaDepartment of Community Health Services, Aga Khan University, Karachi, Pakistan.
Shivaprasad GoudarJawaharlal Nehru Medical College, K.L.E. University, Karnataka, Belgaum, India.
Elwyn ChombaUniversity Teaching Hospital, Lusaka, Zambia.
Archana PatelLata Medical Research Foundation, Maharashtra, Nagpur, India.
Fernando AlthabeInstitute for Clinical Effectiveness, Buenos Aires, Argentina.
Ana GarcesMultidisciplinary Health Institute, Francisco Marroquin University, Guatemala City, Guatemala.
Elizabeth M McClureResearch Triangle Institute International, Durham, North Carolina.
Sarah SaleemDepartment of Community Health Services, Aga Khan University, Karachi, Pakistan.
Fabian EsamaiDepartment of Child Health and Paediatrics, Moi University School of Medicine, Eldoret, Kenya.
Bhala S KodkanyJawaharlal Nehru Medical College, K.L.E. University, Karnataka, Belgaum, India.
Jose M BelizanInstitute for Clinical Effectiveness, Buenos Aires, Argentina.
Richard J DermanChristiana Care Health System, Wilmington, Delaware.
Patricia L HibberdDivsion of Global Health, Massachusetts General Hospital, Boston, Massachusetts.
Nancy KrebsDepartment of Pediatrics, University of Colorado, Denver, Colorado.
Pierre BuekensSchool of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana.
Robert L GoldenbergColumbia University, New York, New York.
Waldemar A CarloDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.
Dennis WallaceResearch Triangle Institute International, Durham, North Carolina.
Janet MooreResearch Triangle Institute International, Durham, North Carolina.
Marion Koso-ThomasNational Institute of Child Health and Human Development, Bethesda, Maryland.
Linda L WrightNational Institute of Child Health and Human Development, Bethesda, Maryland.
Edward A LiechtyDepartment of Pediatrics, Riley Hospital, Indiana University, Indianapolis, Indiana.
Moi University · KERTI International · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USInstituto de Efectividad Clínica y Sanitaria · ARKLE University · INAga Khan University · PKAga Khan University · TZChristiana Care Health System · USColumbia University · USIndiana University – Purdue University Indianapolis · USLata Medical Research Foundation · INMassachusetts General Hospital · USTulane University · USUniversidad Francisco Marroquín · GTUniversity of Alabama at Birmingham · USUniversity of Colorado Denver · USUniversity Teaching Hospital · ZM

Funding

Zika in Pregnancy Supplemental Funding requestU01HD040636 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MCCLURE, ELIZABETH M · 2001 to 2017
$37.5M
UAB/AKU Global Network Research UnitU01HD040607 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOLDENBERG, ROBERT L · 2001 to 2012
$8.5M
Complementary feeding: a Global Network cluster randomized controlled trialU01HD040657 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL · 2001 to 2012
$8.1M
UMKC-JNMC Global Network for Women's and Children's Health Research UnitU01HD042372 · NICHD · UNIVERSITY OF MISSOURI KANSAS CITY · PI DERMAN, RICHARD J · 2001 to 2012
$6.9M
Neonatal Resuscitation in Developing CountriesU01HD043464 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 2003 to 2012
$6.6M
Evidence-Based Global Health Interventions for Mothers and Children, ArgentinaU01HD040477 · NICHD · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI BUEKENS, PIERRE · 2001 to 2013
$5.6M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL, KREBS, NANCY F · 2013 to 2017
$5.1M
Global Network for Women's and Children's Health ResearchU10HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI LIECHTY, EDWARD A. · 2013 to 2017
$4.1M
Improving Quality of Care for the Treatment of Childhood PneumoniaU01HD058322 · NICHD · TUFTS UNIVERSITY BOSTON · PI HIBBERD, PATRICIA L · 2008 to 2012
$4.0M
CCHS-JNMC Global Network for Women's & Children's Health Research UnitU10HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI DERMAN, RICHARD J · 2013 to 2017
$3.7M
Global Network for Women's and Children's HealthU01HD058326 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI LIECHTY, EDWARD A. · 2008 to 2012
$3.6M
NICHD NIH HHS U01 HD040477NICHD NIH HHS U01 HD040607NICHD NIH HHS U01 HD040636NICHD NIH HHS U01 HD040657NICHD NIH HHS U01 HD042372NICHD NIH HHS U01 HD043464NICHD NIH HHS U01 HD058322NICHD NIH HHS U01 HD058326NICHD NIH HHS U10 HD076457NICHD NIH HHS U10 HD076461NICHD NIH HHS U10 HD076474NICHD NIH HHS U10 HD078438NICHD NIH HHS U10 HD078439NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076474
6 · The paper itself

Abstract

aimTo determine the rates of multiple gestation, stillbirth, and perinatal and neonatal mortality and to determine health care system characteristics related to perinatal mortality of these pregnancies in low- and middle-income countries.

methodsPregnant women residing within defined geographic boundaries located in six countries were enrolled and followed to 42 days postpartum.

resultsMultiple gestations were 0.9% of births. Multiple gestations were more likely to deliver in a health care facility compared with singletons (70 and 66%, respectively, p < 0.001), to be attended by skilled health personnel (71 and 67%, p < 0.001), and to be delivered by cesarean (18 versus 9%, p < 0.001). Multiple-gestation fetuses had a relative risk (RR) for stillbirth of 2.65 (95% confidence interval [CI] 2.06, 3.41) and for perinatal mortality rate (PMR) a RR of 3.98 (95% CI 3.40, 4.65) relative to singletons (both p < 0.0001). Neither delivery in a health facility nor the cesarean delivery rate was associated with decreased PMR. Among multiple-gestation deliveries, physician-attended delivery relative to delivery by other health providers was associated with a decreased risk of perinatal mortality.

conclusionsMultiple gestations contribute disproportionately to PMR in low-resource countries. Neither delivery in a health facility nor the cesarean delivery rate is associated with improved PMR.

Indexed as

Perinatal MortalityAdultDeveloping CountriesFemaleGlobal HealthHumansInfant MortalityInfant, NewbornMalePregnancyPregnancy, MultiplePregnancy OutcomePregnancy, TwinRiskStillbirthYoung Adult

Identifiers

PMID23512321
PMCPMC4013719
OpenAlexW2033261434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.