ArticleJournal of molecular evolution2013
The evolutionary origin of biological function and complexity.
Article in Journal of molecular evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Acytota and the evolution of complexity.European biophysics journal : EBJ · 2025Review
- Origins of Life: The Protein Folding Problem all over again?Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Darwinian evolution as a dynamical principle.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- On the Chemical Origin of Biological Cognition.Life (Basel, Switzerland) · 2022Article
- The Origin(s) of Cell(s): Pre-Darwinian Evolution from FUCAs to LUCA : To Carl Woese (1928-2012), for his Conceptual Breakthrough of Cellular Evolution.Journal of molecular evolution · 2021Article
- On the conditions for mimicking natural selection in chemical systems.Nature reviews. Chemistry · 2020Review
- Roadmap to Building a Cell: An Evolutionary Approach.Frontiers in bioengineering and biotechnology · 2020Article
- Systems protobiology: origin of life in lipid catalytic networks.Journal of the Royal Society, Interface · 2018Review
- Processes and patterns of interaction as units of selection: An introduction to ITSNTS thinking.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- The Logic of Life.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2016Article
- Coupled phases and combinatorial selection in fluctuating hydrothermal pools: a scenario to guide experimental approaches to the origin of cellular life.Life (Basel, Switzerland) · 2015Article
- Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics.Open biology · 2013Review
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Abstract
The identification of dynamic kinetic stability (DKS) as a stability kind that governs the evolutionary process for both chemical and biological replicators, opens up new avenues for uncovering the chemical basis of biological phenomena. In this paper, we utilize the DKS concept to explore the chemical roots of two of biology's central concepts--function and complexity. It is found that the selection rule in the world of persistent replicating systems--from DKS less stable to DKS more stable--is the operational law whose very existence leads to the creation of function from of a world initially devoid of function. The origin of biological complexity is found to be directly related to the origin of function through an underlying connection between the two phenomena. Thus the emergence of both function and complexity during abiogenesis, and their growing expression during biological evolution, are found to be governed by the same single driving force, the drive toward greater DKS. It is reaffirmed that the essence of biological phenomena can be best revealed by uncovering biology's chemical roots, by elucidating the physicochemical principles that governed the process by which life on earth emerged from inanimate matter.
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