ArticleParasitology research2013
Evaluation of the diagnostic efficacy of Fasciola adult worm vomit for serodiagnosis of human fasciolosis.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
The diagnostic efficacy of Fasciola gigantica adult worm vomit (AWV) preparation in diagnosis of human fasciolosis was evaluated using conventional enzyme-linked immunosorbent assay (ELISA) and Falcon assay screening test (FAST)-ELISA in comparison with F. gigantica adult total soluble extract (TSE). Sera of fasciolosis patients, patients with other parasitic diseases (hydatid disease, schistosomiasis, toxoplasmosis, and amebiasis), and sera of healthy individuals were enrolled in this study. The results showed that the sensitivity of both conventional ELISA and FAST-ELISA was improved from 95 % using TSE to 100 % when using AWV. The specificity of conventional ELISA was 93.3 % using TSE and increased to 96.7 % using AWV. The specificity of FAST-ELISA using TSE was 96.7 % and became 100 % AWV antigen. The diagnostic accuracy of conventional ELISA was 94 % using TSE and increased to 98 % using AWV. The diagnostic accuracy of FAST-ELISA was 96 % using TSE and increased to 100 % using AWV. It is concluded that both TSE and AWV antigenic preparations are efficient for use in the serodiagnosis of human fasciolosis.
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