ArticleBritish journal of cancer2013
A retrospective observational study of the relationship between family history and survival from colorectal cancer.
Article in British journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Family History of Cancer as Potential Prognostic Factor in Stage III Colorectal Cancer: a Retrospective Monoinstitutional Study.Journal of gastrointestinal cancer · 2020Trial
- Diagnostic and Therapeutic Management of Early Colorectal Cancer.Visceral medicine · 2023Review
- Association between family history and prognosis of patients with colorectal cancer: a systematic review and meta-analysis.Translational cancer research · 2022Article
- Prognostic and Diagnostic Values of miR-506 and SPON 1 in Colorectal Cancer with Clinicopathological Considerations.Journal of gastrointestinal cancer · 2021Article
- Family history of colorectal cancer and survival: a Swedish population-based study.Journal of internal medicine · 2020Article
- Predicting systemic spread in early colorectal cancer: Can we do better?World journal of gastroenterology · 2019Review
- Association of Family History With Cancer Recurrence, Survival, and the Incidence of Colorectal Adenoma in Patients With Colorectal Cancer.Journal of cancer prevention · 2019Article
- Prognostic impact of family history of cancer in Southern Chinese patients with esophageal squamous cell cancer.Journal of Cancer · 2019Article
- Association of family history and survival in patients with colorectal cancer: a pooled analysis of eight epidemiologic studies.Cancer medicine · 2018Article
- Family history of cancer and head and neck cancer survival.The Laryngoscope · 2017Article
- Risk of Second Cancer in Hodgkin Lymphoma Survivors and Influence of Family History.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Article
- Survival in familial colorectal cancer: a Danish cohort study.Familial cancer · 2015Article
- Familial colorectal cancer screening: When and what to do?World journal of gastroenterology · 2015Review
- Observational
- Family history of colorectal cancer is not associated with colorectal cancer survival regardless of microsatellite instability status.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014Article
- Familial colorectal cancer: a review.World journal of gastroenterology · 2014Review
- Prognostic impact of family history in southern Chinese patients with undifferentiated nasopharyngeal carcinoma.British journal of cancer · 2013Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlthough family history is well established to be a risk factor for developing colorectal cancer (CRC), much less is known about its impact on patient survival. This study aimed to link CRC patient data from the National Study of Colorectal Cancer Genetics (NSCCG) to the National Cancer Data Repository (NCDR) to examine the relationship between family history and the characteristics and outcomes of CRC.
methodsAll eligible NSCCG patients underwent a matching process to the NCDR using combinations of their personal identifiers. The characteristics and survival of CRC patients with and without a family history of CRC were compared.
resultsOf the 10 937 NSCCG patients eligible to be matched into the NCDR, 10 782 (98.6%) could be fully linked. There were no significant differences between those with and without a family history of CRC (defined as having at least one affected first-degree relative) in terms of age, sex, tumour stage at diagnosis, presence of multiple cancers, mode of presentation to hospital and surgical management, although patients with familial CRC were more likely to have right-sided tumours (P<0.01). The survival of patients with familial CRC was significantly better than those with sporadic CRC (HR 0.89, 95%CI: 0.81-0.98, P=0.02).
conclusionWe have demonstrated that it is possible to robustly match patients recruited into the NSCCG into the NCDR and, by using this record linkage, enable genetic data to be related to CRC phenotype, clinical management and outcome. This study provides evidence that a family history of CRC is associated with better survival after a diagnosis of CRC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.