ArticleLab on a chip2013
Optoacoustic tweezers: a programmable, localized cell concentrator based on opto-thermally generated, acoustically activated, surface bubbles.
Article in Lab on a chip, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 76 citations in OpenAlex.
- Photothermal Transport for Guiding Nanoparticles Through the Vitreous Humor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Light-Driven, Dynamic Assembly of Micron-To-Centimeter Parts, Micromachines and Microbot Swarms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Light-driven soft microrobots based on hydrogels and LCEs: development and prospects.RSC advances · 2024Review
- Exploiting Sound for Emerging Applications of Extracellular Vesicles.Nano research · 2024Article
- Hypothermal opto-thermophoretic tweezers.Nature communications · 2023Article
- Manipulation with sound and vibration: A review on the micromanipulation system based on sub-MHz acoustic waves.Ultrasonics sonochemistry · 2023Review
- Review
- Hypothermal opto-thermophoretic tweezers.Research square · 2023Article
- Noninvasive prenatal diagnosis targeting fetal nucleated red blood cells.Journal of nanobiotechnology · 2022Review
- Review of Bubble Applications in Microrobotics: Propulsion, Manipulation, and Assembly.Micromachines · 2022Review
- Heat-Mediated Optical Manipulation.Chemical reviews · 2022Review
- Considerations of Antibody Geometric Constraints on NK Cell Antibody Dependent Cellular Cytotoxicity.Frontiers in immunology · 2020Review
- Acoustofluidic methods in cell analysis.Trends in analytical chemistry : TRAC · 2019Article
- Manipulation of micro-objects using acoustically oscillating bubbles based on the gas permeability of PDMS.Biomicrofluidics · 2018Article
- A rapid co-culture stamping device for studying intercellular communication.Scientific reports · 2016Article
- Probing Cell Deformability via Acoustically Actuated Bubbles.Small (Weinheim an der Bergstrasse, Germany) · 2016Article
- Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device.Scientific reports · 2015Article
- Get to Understand More from Single-Cells: Current Studies of Microfluidic-Based Techniques for Single-Cell Analysis.International journal of molecular sciences · 2015Review
- Efficient single-cell poration by microsecond laser pulses.Lab on a chip · 2015Article
- Two-bubble acoustic tweezing cytometry for biomechanical probing and stimulation of cells.Biophysical journal · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
We present a programmable, biocompatible technique for dynamically concentrating and patterning particles and cells in a microfluidic device. Since our technique utilizes opto-thermally generated, acoustically activated, surface bubbles, we name it "optoacoustic tweezers". The optoacoustic tweezers are capable of concentrating particles/cells at any prescribed locations in a microfluidic chamber without the use of permanent structures, rendering it particularly useful for the formation of flexible, complex cell patterns. Additionally, this technique has demonstrated excellent biocompatibility and can be conveniently integrated with other microfluidic units. In our experiments, micro-bubbles were generated by focusing a 405 nm diode laser onto a gold-coated glass chamber. By properly tuning the laser, we demonstrate precise control over the position and size of the generated bubbles. Acoustic waves were then applied to activate the surface bubbles, causing them to oscillate at an optimized frequency. The resulting acoustic radiation force allowed us to locally trap particles/cells, including 15 μm polystyrene beads and HeLa cells, around each bubble. Cell-adhesion tests were also conducted after cell concentrating to confirm the biocompatibility of this technique.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.