Evidence map›Paper›PMID 23510937›Full record

ArticleThe Libyan journal of medicine2013

Candida colonisation in asymptomatic HIV patients attending a tertiary hospital in Benin City, Nigeria.

Newton O Esebelahie, Ifeoma B Enweani, Richard Omoregie

Open access · goldAbstract read
In one paragraph

Article in The Libyan journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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  4. Intestinal microbiota: The hidden gems in the gut?Asian Pacific journal of allergy and immunology · 2020
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  6. Mycobiome in the Gut: A Multiperspective Review.Mediators of inflammation · 2020
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  9. Article
  10. Isolation and evaluation ofAfrican health sciences · 2017
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Gut microbes
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Newton O EsebelahieDepartment of Medical Laboratory Science, Faculty of Health Sciences and Technology, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Nigeria. newtonesebelahie@yahoo.com
Ifeoma B Enweani
Richard Omoregie
Nnamdi Azikiwe University · NGUniversity of Benin Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandidiasis is the commonest opportunistic fungal infection in patients infected with human immunodeficiency virus (HIV). CD4+ lymphocyte counts have been found to be a marker of HIV disease progression.

aimThis study focused on determining the spectrum of Candida isolates in urine, stool, and oral specimens among HIV patients in a tertiary hospital.

methodsA total of 300 subjects comprising of 200 HIV patients and 100 non-HIV subjects were used for this study. Three samples (urine, stool, and oral swab) were collected from each subject. Each specimen was processed using standard microbiological techniques and emergent Candida isolates were identified with CHROMagar™ Candida and sugar fermentation tests.

resultsThe overall prevalence of Candida colonisation among HIV patients was 52.5%. HAART-naive patients had a significantly higher prevalence (OR = 3.65; 95% CI = 2.03-6.56; p<0.0001) than their counterpart on highly active antiretroviral therapy (HAART) (OR = 1.99; 95% CI = 1.13-3.50; p=0.0232). Female gender was a significant risk factor for acquiring Candida infection (OR = 3.40; 95% CI = 1.14-10.13; p=0.0289). The effect of age on prevalence of candidiasis was observed among HIV patients on HAART (p=0.0161). A CD4+ count <200 cells/µl was a significant risk factor for acquiring candidal infection only among HAART-naive patients (OR = 4.37; 95% CI = 1.60-11.95; p=0.0042). The five species of Candida recovered from this study were C. albicans, C. krusei, C. parapsilosis, C. tropicalis, and C. glabrata.

conclusionThere is a significant relationship between antiretroviral therapy, CD4+ counts, and the prevalence of candidiasis.

Indexed as

AdultAgedAge FactorsAntiretroviral Therapy, Highly ActiveCandidaCandidiasisCase-Control StudiesFecesFemaleHIV InfectionsHumansMaleMiddle AgedMouth MucosaNigeriaRisk FactorsCandida colonisationCD4+ countsHAARTHAART-naiveprevalence

Identifiers

PMID23510937
PMCPMC3602435
OpenAlexW2083080080

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.