ArticleEpidemiology and infection2013
Experimental infection of dogs with H3N2 canine influenza virus from China.
Article in Epidemiology and infection, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- The biological characteristics and infection dynamics of a novel H3N2 canine influenza virus genotype in beagles.Virology journal · 2024Article
- Comparison of Pathogenicity of Different Infectious Doses of H3N2 Canine Influenza Virus in Dogs.Frontiers in veterinary science · 2020Article
- Comparison of the virulence of three H3N2 canine influenza virus isolates from Korea and China in mouse and Guinea pig models.BMC veterinary research · 2018Article
- Comparison of the virulence and transmissibility of canine H3N2 influenza viruses and characterization of their canine adaptation factors.Emerging microbes & infections · 2018Article
- Equine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic Divergence.Journal of virology · 2015Article
- Monoclonal antibody specific to HA2 glycopeptide protects mice from H3N2 influenza virus infection.Veterinary research · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Canine influenza virus (CIV) is an emerging pathogen that causes acute respiratory disease in dogs. The aim of this study was to investigate the pathogenicity of A/canine/Jiangsu/06/2010 (H3N2) virus isolated in China. Nine dogs were inoculated intranasally with 107.95 of 50% egg infectious dose (EID50) of the virus. The onset of clinical signs and virus shedding was observed on day 1 post-infection (p.i.). The peak clinical score occurred between days 4 and 6 p.i. The experimentally infected dogs were found to shed virus not only via the respiratory tract but also via the digestive tract. Viral RNA could be detected in multiple organs including the trachea, lung, liver, spleen, kidney, brain and duodenum. All the sampled organs from infected dogs showed significant lesions and viral antigen staining. The results differed from those reporting using previous CIV strains; the Chinese isolate could induce extrapulmonary infection and cause extensive lesions in dogs.
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