ArticleCardiovascular diabetology2013
Co-morbidity but not dysglycaemia reduces quality of life in patients with type-2 diabetes treated with oral mono- or dual combination therapy--an analysis of the DiaRegis registry.
Article in Cardiovascular diabetology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Health state utility values of type 2 diabetes mellitus and related complications: a systematic review and meta-regression.Health and quality of life outcomes · 2024Pooled it
- Patient-Reported Outcome Measures in Registry-Based Studies of Type 2 Diabetes Mellitus: a Systematic Review.Current diabetes reports · 2019Pooled it
- Epidemiology and Burden of Peripheral Artery Disease in People With Type 2 Diabetes: A Systematic Literature Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Review
- Implications of Patient-Reported Outcome Measures among patients with recently diagnosed type 2 diabetes.Israel journal of health policy research · 2024Article
- MorbiNet: multimorbidity networks in adult general population. Analysis of type 2 diabetes mellitus comorbidity.Scientific reports · 2020Article
- Impact of type 2 diabetes treated with non-insulin medication and number of diabetes-coexisting diseases on EQ-5D-5 L index scores in the Finnish population.Health and quality of life outcomes · 2019Article
- Patient work from a context and time use perspective: a mixed-methods study protocol.BMJ open · 2018Observational
- Is guideline-adherent prescribing associated with quality of life in patients with type 2 diabetes?PloS one · 2018Article
- Health-Related Quality of Life and its Determinants Among Women With Diabetes Mellitus: A Cross-Sectional Analysis.Nursing and midwifery studies · 2016Article
- Awareness, treatment and control of cardiometabolic disorders in Chinese adults with diabetes: a national representative population study.Cardiovascular diabetology · 2015Article
- Relationship between chronic complications, hypertension, and health-related quality of life in Portuguese patients with type 2 diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2015Article
- The role of co-morbidity in the selection of antidiabetic pharmacotherapy in type-2 diabetes.Cardiovascular diabetology · 2013Review
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Authors and funding
8 authors.
Funding
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Abstract
backgroundType-2 diabetes mellitus has a major impact on health related quality of life (HRQoL). We aimed to identify patient and treatment related variables having a major impact.
methodsDiaRegis is a prospective diabetes registry. The EQ-5D was used to describe differences in HRQoL at baseline. Odds ratios (OR) with 95% confidence intervals (CI) were determined from univariable regression analysis. For the identification of independent predictors of a low score on the EQ-5D, multivariable unconditional logistic regression analysis was performed.
resultsA total of 2,760 patients were available for the present analysis (46.7% female, median age 66.2 years). Patients had considerable co-morbidity (18.3% coronary artery disease, 10.6% heart failure, 5.9% PAD and 5.0% stroke/TIA). Baseline HbA1c was 7.4%, fasting- and postprandial plasma glucose 139 mg/dl and 183 mg/dl.The median EQ-5D was 0.9 (interquartile range [IQR] 0.8-1.0). Independent predictors for a low EQ-5D were age > 66 years (OR 1.49; 95%CI 1.08-2.06), female gender (2.11; 1.55-2.86), hypertension (1.73; 1.03-2.93), peripheral neuropathy (1.62; 0.93-2.84) and clinically relevant depression (11.01; 3.97-30.50). There was no influence of dysglycaemia on the EQ-5D score.
conclusionThe present study suggests, that co-morbidity but not average glycaemic control reduces health related quality of life in type 2 diabetes mellitus.
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