ArticleBioMed research international2013
Vaccine adverse events reported during the first ten years (1998-2008) after introduction in the state of Rondonia, Brazil.
Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review on Yellow Fever Vaccine and Adverse Events.Global health, epidemiology and genomics · 2026Pooled it
- Reporting profile of adverse events following DTaP-IPV/Hib pentavalent vaccine: A 13-year real-world surveillance data analysis.Human vaccines & immunotherapeutics · 2025Article
- Article
- Adverse Events Following Immunizations in Infants Under 1 Year of Age in Lorestan Province, Western Iran.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- Adverse events following immunization associated with coronavirus disease 2019 (COVID-19) vaccines: A descriptive analysis from VigiAccess.Human vaccines & immunotherapeutics · 2022Article
- Protectivity and safety following recombinant hepatitis B vaccine with different source of bulk compared to hepatitis B (Bio Farma) vaccine in Indonesia.Clinical and experimental vaccine research · 2022Article
- Epidemiological study of adverse events following immunization in under 5 year children.Journal of family medicine and primary care · 2021Article
- The Comparison of the Adverse Events of Pentavalent Vaccine and DPT Vaccine in 2-6 Months Infants in Iran: A National Study.Annals of global health · 2020Article
- Adverse events following immunisation (AEFI) reports from the Zimbabwe expanded programme on immunisation (ZEPI): an analysis of spontaneous reports in Vigibase® from 1997 to 2017.BMC public health · 2019Article
- Use of electronic immunization registry in the surveillance of adverse events following immunization.Revista de saude publica · 2018Article
- [Analysis of the Vaccine Adverse Event Reporting System in Brazil, 2014 to 2016Análisis del Sistema de Información de Vigilancia de Eventos Adversos Posvacunación en Brasil, 2014 a 2016].Revista panamericana de salud publica = Pan American journal of public health · 2018Article
- Parental Approach to the Prevention and Management of Fever and Pain Following Childhood Immunizations: A Survey Study.Clinical pediatrics · 2017Article
- Knowledge, Perceptions, and Practice of Nurses on Surveillance of Adverse Events following Childhood Immunization in Nairobi, Kenya.BioMed research international · 2016Article
- Factors associated with the exposure of vaccines to adverse temperature conditions: the case of North West region, Cameroon.BMC research notes · 2015Article
- Safety, immunization coverage and determinants of a new kind of Hepatitis B vaccine firstly applied in Ningbo, China.Human vaccines & immunotherapeutics · 2015Article
- The Ontology of Vaccine Adverse Events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccines.Journal of biomedical semantics · 2013Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite good safety records, vaccines given to young children can cause adverse events. We investigated the reported adverse events following immunization (AEFI) of vaccines given to children of less than seven years of age during the first ten years (1998 to 2008) in the state of Rondonia, Brazil. We worked with the events related to BCG (Bacillus Calmett-Guérin), HB (hepatitis B), DTwP/Hib (diphtheria-tetanus-pertussis+Hemophillus influenza b), DTP (diphtheria-tetanus-pertussis), MMR (mumps, measles, rubella), and YF (yellow fever) vaccines because they were part of the recommended scheme. The number of doses of vaccines given was 3,231,567 with an average of AEFI of 57.2/year during the studied period. DTwP/Hib was responsible for 298 (57.8%), DTP 114 (22.9%), HB 31 (6%), MMR 28 (5.4%), BCG 24 (4.7%), and YF 20 (3.9%) of the reported AEFI. The combination of the AEFI for DTwP/Hib vaccines showed the highest number of systemic (61.4%) and local events (33.8%). Young children (≤1-year old) were more susceptible to AEFI occurring in the 6 hours (54.2%) following vaccine uptake. This study suggests significant differences in reactogenicity of vaccines and that despite limitations of the AEFI Brazilian registry system we cannot ignore underreporting and should use the system to expand our understanding of adverse events and effects.
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