Evidence map›Paper›PMID 23509731›Full record

ReviewBioMed research international2013

What is recent in pancreatic cancer immunotherapy?

Elena Niccolai, Domenico Prisco, Mario Milco D'Elios, Amedeo Amedei

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. New targeted therapies in pancreatic cancer.World journal of gastroenterology · 2015
    Review
  8. Gastric cancer and the epoch of immunotherapy approaches.World journal of gastroenterology · 2015
    Review
  9. Pancreatic cancer, treatment options, and GI-4000.Human vaccines & immunotherapeutics · 2015
    Review
  10. Review
  11. Pancreatic cancer, treatment options, and GI-4000.Human vaccines & immunotherapeutics · 2014
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elena NiccolaiDepartment of Internal Medicine, University of Florence and Patologia Medica Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
Domenico Prisco
Mario Milco D'Elios
Amedeo Amedei
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer (PC) represents an unresolved therapeutic challenge, due to the poor prognosis and the reduced response to currently available treatments. Pancreatic cancer is the most lethal type of digestive cancers, with a median survival of 4-6 months. Only a small proportion of PC patients is curative by surgical resection, whilst standard chemotherapy for patients in advanced disease generates only modest effects with considerable toxic damages. Thus, new therapeutic approaches, specially specific treatments such as immunotherapy, are needed. In this paper we analyze recent preclinical and clinical efforts towards immunotherapy of pancreatic cancer, including passive and active immunotherapy approaches, designed to target pancreatic-cancer-associated antigens and to elicit an antitumor response in vivo.

Indexed as

Antibodies, MonoclonalCancer VaccinesClinical Trials as TopicCombined Modality TherapyDendritic CellsHumansImmunotherapyMedical OncologyPancreatic NeoplasmsPeptidesPrognosisT-LymphocytesTreatment OutcomeAntibodies, MonoclonalCancer VaccinesPeptides

Identifiers

PMID23509731
PMCPMC3591222
OpenAlexW2054429635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.