ArticleSarcoma2013
Can bone tissue engineering contribute to therapy concepts after resection of musculoskeletal sarcoma?
Article in Sarcoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Soft Tissue Reconstruction and Integration to Implant After Bone-Tumor Resection: A Current Concept Review.Current oncology (Toronto, Ont.) · 2024Review
- A scientometric and visualization analysis of 3D printing scaffolds for vascularized bone tissue engineering over the last decade.Regenerative therapy · 2024Review
- Long-term in vitro degradation and in vivo evaluation of resorbable bioceramics.Journal of materials science. Materials in medicine · 2021Article
- Graphene and its Derivatives for Bone Tissue Engineering:Frontiers in bioengineering and biotechnology · 2021Review
- 3D-Printing of Hierarchically Designed and Osteoconductive Bone Tissue Engineering Scaffolds.Materials (Basel, Switzerland) · 2020Article
- Scaffolds and coatings for bone regeneration.Journal of materials science. Materials in medicine · 2020Review
- Reconstructive Science in Orthopedic Oncology.Techniques in orthopaedics (Rockville, Md.) · 2018Article
- Article
- [Scaffold-based Bone Tissue Engineering].Der Orthopade · 2017Review
- Transformation of Breast Reconstruction via Additive Biomanufacturing.Scientific reports · 2016Article
- A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects.Biotechnology journal · 2015Article
- Customised osteotomy guides and endoprosthetic reconstruction for periacetabular tumours.International orthopaedics · 2014Article
- Bone Regeneration Based on Tissue Engineering Conceptions - A 21st Century Perspective.Bone research · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resection of musculoskeletal sarcoma can result in large bone defects where regeneration is needed in a quantity far beyond the normal potential of self-healing. In many cases, these defects exhibit a limited intrinsic regenerative potential due to an adjuvant therapeutic regimen, seroma, or infection. Therefore, reconstruction of these defects is still one of the most demanding procedures in orthopaedic surgery. The constraints of common treatment strategies have triggered a need for new therapeutic concepts to design and engineer unparalleled structural and functioning bone grafts. To satisfy the need for long-term repair and good clinical outcome, a paradigm shift is needed from methods to replace tissues with inert medical devices to more biological approaches that focus on the repair and reconstruction of tissue structure and function. It is within this context that the field of bone tissue engineering can offer solutions to be implemented into surgical therapy concepts after resection of bone and soft tissue sarcoma. In this paper we will discuss the implementation of tissue engineering concepts into the clinical field of orthopaedic oncology.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.