ArticleAnnals of the American Thoracic Society2013
Use of noninvasive ventilation in patients with acute respiratory failure, 2000-2009: a population-based study.
Article in Annals of the American Thoracic Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07157215 (An International Survey on the Use of NIV Outside the ICU), which is not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An International Survey on the Use of NIV Outside the ICU (NIV-Safety Study)
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Comparison of clinical outcomes between high-flow nasal cannula and non-invasive ventilation in acute exacerbation of COPD: a meta-analysis of randomized controlled trials.BMC pulmonary medicine · 2025Pooled it
- Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial.Critical care (London, England) · 2021Trial
- Trial
- Hospital patterns of mechanical ventilation for patients with exacerbations of COPD.Annals of the American Thoracic Society · 2015Trial
- Factors Associated with Outcomes of Non-Invasive Ventilation in Acute Hypercapnic Respiratory Failure with Acidosis: A Study from a Tertiary Care Hospital in Pakistan.Journal of clinical medicine · 2026Article
- Use of noninvasive positive pressure ventilation in patients admitted to the internal medicine service of a tertiary care hospital.BMC research notes · 2026Article
- Changes of respiratory microbiota associated with prognosis in pulmonary infection patients with invasive mechanical ventilation-supported respiratory failure.Annals of medicine · 2025Article
- Impact of Educational Intervention on NIMV: 'Impact of Educational Intervention on Noninvasive Ventilation (NIV) in Nurses and Students'.The clinical teacher · 2025Article
- Role of Non-Invasive Ventilation in Elderly Patients: Therapeutic Opportunity or Medical Futility? An Updated Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Trends in use of intensive care during hospitalizations at the end-of-life among older adults with advanced cancer.Journal of the American Geriatrics Society · 2024Article
- Analgesia and Sedation Use During Noninvasive Ventilation for Acute Respiratory Failure.Critical care medicine · 2024Article
- Noninvasive respiratory support in the emergency department: Controversies and state-of-the-art recommendations.Journal of the American College of Emergency Physicians open · 2024Review
- Outcomes of Acute Respiratory Failure in Patients With Cancer in the United States.Mayo Clinic proceedings · 2024Review
- Noninvasive vs invasive respiratory support for patients with acute hypoxemic respiratory failure.PloS one · 2024Observational
- Safety and efficacy of noninvasive ventilation for acute respiratory failure in general medical ward: a prospective cohort study.Journal of thoracic disease · 2023Article
- Delayed intubation associated with in-hospital mortality in patients with COVID-19 respiratory failure who fail heated and humified high flow nasal canula.BMC anesthesiology · 2023Observational
- Predicting Failure of Noninvasive Respiratory Support Using Deep Recurrent Learning.Respiratory care · 2023Observational
- Development of a prognostic nomogram for sepsis associated-acute respiratory failure patients on 30-day mortality in intensive care units: a retrospective cohort study.BMC pulmonary medicine · 2023Article
- Decline in Prolonged Acute Mechanical Ventilation, 2011-2019.American journal of respiratory and critical care medicine · 2022Article
- ARDS associated acute brain injury: from the lung to the brain.European journal of medical research · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
rationaleAlthough evidence supporting use of noninvasive ventilation (NIV) during acute exacerbations of chronic obstructive pulmonary disease (COPD) is strong, evidence varies widely for other causes of acute respiratory failure.
objectivesTo compare utilization trends and outcomes associated with NIV in patients with and without COPD.
methodsWe identified 11,659,668 cases of acute respiratory failure from the Nationwide Inpatient Sample during years 2000 to 2009 and compared NIV utilization trends and failure rates for cases with or without a diagnosis of COPD. MEASUREMENTS AND MAIN
resultsThe proportion of patients with COPD who received NIV increased from 3.5% in 2000 to 12.3% in 2009 (250% increase), and the proportion of patients without COPD who received NIV increased from 1.2% in 2000 to 6.0% in 2009 (400% increase). The rate of increase in the use of NIV was significantly greater for patients without COPD (18.1% annual change) than for patients with COPD (14.3% annual change; P = 0.02). Patients without COPD were more likely to have failure of NIV requiring endotracheal intubation (adjusted odds ratio, 1.19; 95% confidence interval, 1.15-1.22; P < 0.0001). Patients in whom NIV failed had higher hospital mortality than patients receiving mechanical ventilation without a preceding trial of NIV (adjusted odds ratio, 1.14; 95% confidence interval, 1.11-1.17; P < 0.0001).
conclusionThe use of NIV during acute respiratory failure has increased at a similar rate for all diagnoses, regardless of supporting evidence. However, NIV is more likely to fail in patients without COPD, and NIV failure is associated with increased mortality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.