ReviewStem cells (Dayton, Ohio)2013
Concise review: Current concepts in bone marrow microenvironmental regulation of hematopoietic stem and progenitor cells.
Review in Stem cells (Dayton, Ohio), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Differential effects of fetal bovine serum and human platelet lysate on mesenchymal stromal cell-mediated support of hematopoietic stem/progenitor cells: a functional and transcriptomic analysis.Stem cell research & therapy · 2025Article
- Interactions of Hematopoietic and Associated Mesenchymal Stem Cell Populations in the Bone Marrow Microenvironment, In Vivo and In Vitro Model.International journal of molecular sciences · 2025Review
- Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring.Cell reports · 2023Article
- In Vitro Models of Bone Marrow Remodelling and Immune Dysfunction in Space: Present State and Future Directions.Biomedicines · 2022Review
- Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia.Journal of immunology research · 2022Article
- Elevation of Peripheral Blood CD34+ and Platelet Levels After Exercise With Cooling and Compression.Arthroscopy, sports medicine, and rehabilitation · 2021Article
- Article
- Role ofFrontiers in cell and developmental biology · 2021Review
- The Expression of MicroRNA-21 in Bone Marrow Fluid is an Indicator of Hematological Disorders and Mortality.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation.PLoS computational biology · 2019Article
- Tissue engineering in pediatric urology - a critical appraisal.Innovative surgical sciences · 2018Review
- Bone marrow laminins influence hematopoietic stem and progenitor cell cycling and homing to the bone marrow.Matrix biology : journal of the International Society for Matrix Biology · 2018Article
- Good, Bad, or Ugly: the Biological Roles of Bone Marrow Fat.Current osteoporosis reports · 2018Review
- Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro.Scientific reports · 2018Article
- TGF-β Signaling Accelerates Senescence of Human Bone-Derived CD271 and SSEA-4 Double-Positive Mesenchymal Stromal Cells.Stem cell reports · 2018Article
- Splenic myeloid metaplasia in warm autoimmune hemolytic anemia (wAIHA): a retrospective study.Blood research · 2018Article
- Transforming growth factor-β in stem cells and tissue homeostasis.Bone research · 2018Article
- IL-17 Promotes Differentiation of Splenic LSKJournal of immunology (Baltimore, Md. : 1950) · 2017Article
- Donor-Derived Smoldering Multiple Myeloma following a Hematopoietic Cell Transplantation for AML.Case reports in hematology · 2017Article
- Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Hematopoietic stem cell (HSC) behavior is governed in large part by interactions of the blood system with the bone microenvironment. Increasing evidence demonstrates the profound role the local HSC microenvironment or niche plays in normal stem cell function, in therapeutic activation and in the setting of malignancy. A number of cellular and molecular components of the microenvironment have been identified thus far, several of which are likely to provide exciting therapeutic targets in the near future. Clinically effective strategies for niche manipulation, however, require careful study of the interaction of these niche components. Some of the key findings defining these regulatory interactions are explored in this concise review, with special emphasis on potential translational applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.