Evidence map›Paper›PMID 23508883›Full record

ArticleFrontiers in oncology2013

Future vision for the quality assurance of oncology clinical trials.

Thomas J Fitzgerald, Maryann Bishop-Jodoin, Walter R Bosch, Walter J Curran, David S Followill, James M Galvin, Richard Hanusik, Steven R King, Michael V Knopp, Fran Laurie and 8 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. The impact of Clinical Trials Radiographers on set-up and recruitment to radiotherapy trials.Technical innovations & patient support in radiation oncology · 2025
    Article
  3. Review
  4. Review
  5. Quality assurance in radiation oncology.Pediatric blood & cancer · 2021
    Review
  6. Article
  7. The Importance of Imaging in Radiation Oncology for National Clinical Trials Network Protocols.International journal of radiation oncology, biology, physics · 2018
    Review
  8. Article
  9. Imaging and Data Acquisition in Clinical Trials for Radiation Therapy.International journal of radiation oncology, biology, physics · 2016
    Review
  10. Radiation therapy quality assurance in clinical trials--Global Harmonisation Group.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2014
    Article
  11. Advances and future of Radiation Oncology.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Thomas J FitzgeraldQuality Assurance Review Center Lincoln, RI, USA ; Department of Radiation Oncology, University of Massachusetts Medical School Worcester, MA, USA.
Maryann Bishop-Jodoin
Walter R Bosch
Walter J Curran
David S Followill
James M Galvin
Richard Hanusik
Steven R King
Michael V Knopp
Fran Laurie
Elizabeth O'Meara
Jeff M Michalski
Joel H Saltz
Mitchell D Schnall
Lawrence Schwartz
Kenneth Ulin
Ying Xiao
Marcia Urie

Funding

RTOG Foreign AccrualU10CA021661 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI CURRAN, WALTER J. · 1985 to 2013
$150.3M
RADIOLOGICAL PHYSICS CENTERU10CA010953 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FOLLOWILL, DAVID S · 1985 to 2013
$34.5M
QUALITY ASSURANCE REVIEW CENTER (QARC)U10CA029511 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FITZGERALD, THOMAS J. · 1985 to 2013
$23.4M
ADVANCED TECHNOLOGY QA CENTERU24CA081647 · NCI · WASHINGTON UNIVERSITY · PI MICHALSKI, JEFF M. · 1999 to 2013
$22.8M
NCI NIH HHS U10 CA010953NCI NIH HHS U10 CA021661NCI NIH HHS U10 CA029511NCI NIH HHS U24 CA081647
6 · The paper itself

Abstract

The National Cancer Institute clinical cooperative groups have been instrumental over the past 50 years in developing clinical trials and evidence-based process improvements for clinical oncology patient care. The cooperative groups are undergoing a transformation process as we further integrate molecular biology into personalized patient care and move to incorporate international partners in clinical trials. To support this vision, data acquisition and data management informatics tools must become both nimble and robust to support transformational research at an enterprise level. Information, including imaging, pathology, molecular biology, radiation oncology, surgery, systemic therapy, and patient outcome data needs to be integrated into the clinical trial charter using adaptive clinical trial mechanisms for design of the trial. This information needs to be made available to investigators using digital processes for real-time data analysis. Future clinical trials will need to be designed and completed in a timely manner facilitated by nimble informatics processes for data management. This paper discusses both past experience and future vision for clinical trials as we move to develop data management and quality assurance processes to meet the needs of the modern trial.

Indexed as

Clinical Trials Cooperative Group ProgramNational Cancer Instituteoncology clinical trialsquality assuranceradiation oncology

Identifiers

PMID23508883
PMCPMC3598226

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.