Evidence map›Paper›PMID 23508299›Full record

ArticleFrontiers in physiology2013

Endosymbiotic bacteria in insects: guardians of the immune system?

Ioannis Eleftherianos, Jaishri Atri, Julia Accetta, Julio C Castillo

Abstract read
In one paragraph

Article in Frontiers in physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Microbial network assembly in bat flies with differing host specificity from North Africa.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  5. Article
  6. Article
  7. Prevalence of Wolbachia infection in field natural population of the apricot seed wasp Eurytoma samsonowi (Hymenoptera: Eurytomidae).International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  8. Role of microbiota in host-Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. The endosymbiontmBio · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Frontiers in microbiology · 2024
    Article
  17. Gut microbiota in parasite-transmitting gastropods.Infectious diseases of poverty · 2023
    Review
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ioannis EleftherianosInsect Infection and Immunity Lab, Department of Biological Sciences, Columbian College of Arts and Sciences, Institute for Biomedical Sciences, The George Washington University Washington, DC, USA.
Jaishri Atri
Julia Accetta
Julio C Castillo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insects have evolved obligate, mutualistic interactions with bacteria without further transmission to other eukaryotic organisms. Such long-term obligate partnerships between insects and bacteria have a profound effect on various physiological functions of the host. Here we provide an overview of the effects of endosymbiotic bacteria on the insect immune system as well as on the immune response of insects to pathogenic infections. Potential mechanisms through which endosymbionts can affect the ability of their host to resist an infection are discussed in the light of recent findings. We finally point out unresolved questions for future research and speculate how the current knowledge can be employed to design and implement measures for the effective control of agricultural insect pests and vectors of diseases.

Indexed as

endosymbiontimmunityinfectioninsectSpiroplasmaWolbachia

Identifiers

PMID23508299
PMCPMC3597943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.