ArticleBiomatter
The influence of operating parameters on the drug release and antibacterial performances of alginate fibrous dressings prepared by wet spinning.
Article in Biomatter. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Characterization of Sucrose-Impregnated Crystalline Glucose/Mannose Films as Moisturizing Wound Dressings and Their Significant Healing Effect on Deep Wounds in a Rat Model.Bioengineering (Basel, Switzerland) · 2025Article
- Review
- Alginate-Based Bio-Composites and Their Potential Applications.Journal of functional biomaterials · 2022Review
- Bioactive Molecules Release and Cellular Responses of Alginate-Tricalcium Phosphate Particles Hybrid Gel.Nanomaterials (Basel, Switzerland) · 2017Article
- Biotechnologically produced microbial alginate dressings show enhanced gel forming capacity compared to commercial alginate dressings of marine origin.Journal of materials science. Materials in medicine · 2015Article
- Terminal sterilization of alginate hydrogels: efficacy and impact on mechanical properties.Journal of biomedical materials research. Part B, Applied biomaterials · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wet spinning was used to manufacture fibrous alginate hydrogel wound dressings. Samples manufactured using varied operating parameters (decreased air pressure and calcium concentration or increased nozzle diameter and alginate concentration) were compared with the control samples. The changes in the fiber size, Young's modulus, swelling ratio, fetal bovine serum (BSA) release efficacy, water vapor transmission rate (WVTR) and bacterial inhibition potential due to alterations of the operating parameters were measured. The samples manufactured using altered operating parameters had larger fiber sizes (p < 0.05) and lower Young's moduli (p < 0.05). The changes in swelling ratios, BSA release efficacies, WVTR and bacterial inhibition potential showed a significant dependence on the degree of calcium crosslinking of the hydrogel and on how tightly the fibers were bound with one another. By manipulating the operating parameters in the wet-spinning system, wound dressings with different properties were successfully made.
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Registered trials
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