Trial reportCritical care medicine2013
Comparison of sleep quality with mechanical versus spontaneous ventilation during weaning of critically III tracheostomized patients.
Trial report in Critical care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Non-pharmacological interventions for sleep promotion in the intensive care unit.The Cochrane database of systematic reviews · 2015Pooled it
- A meta-analysis of sleep-promoting interventions during critical illness.The American journal of medicine · 2015Pooled it
- Impact of earplugs and eye mask on sleep in critically ill patients: a prospective randomized study.Critical care (London, England) · 2017Trial
- Improving sleep in ICUs through real-time sleep monitoring: a proof-of-concept study.Annals of intensive care · 2026Article
- Article
- Sleep during and following critical illness: A narrative review.World journal of critical care medicine · 2023Review
- Sleep and critical illness: a review.Frontiers in medicine · 2023Review
- Sleep cycle in children with severe acute bronchopneumonia during mechanical ventilation at different depths of sedation.BMC pediatrics · 2022Article
- The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020).Journal of intensive care · 2021Article
- Updated Perspectives on the Management of Sleep Disorders in the Intensive Care Unit.Nature and science of sleep · 2021Review
- Management of tracheostomies in the intensive care unit: a scoping review.BMJ open respiratory research · 2020Article
- Effects of deep sedation on sleep in critically ill medical patients on mechanical ventilation.Journal of sleep research · 2020Article
- Pharmacological and non-pharmacological interventions to promote sleep in intensive care units: a critical review.Sleep & breathing = Schlaf & Atmung · 2020Review
- Sleep in the Intensive Care Unit: Strategies for Improvement.Seminars in respiratory and critical care medicine · 2019Review
- Sleep and Circadian Rhythm in Critical Illness.Critical care (London, England) · 2019Review
- The effects of mechanical ventilation on the quality of sleep of hospitalised patients in the Intensive Care Unit.Romanian journal of anaesthesia and intensive care · 2018Review
- Sleep quality and circadian rhythm disruption in the intensive care unit: a review.Nature and science of sleep · 2017Review
- Positive and negative effects of mechanical ventilation on sleep in the ICU: a review with clinical recommendations.Intensive care medicine · 2016Review
- Sleep disturbance in older ICU patients.Clinical interventions in aging · 2014Review
- To sleep, or not to sleep, that is the question.Critical care medicine · 2013Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn mechanically ventilated patients under mechanical ventilation in the ICU, ventilatory mode or settings may influence sleep quality. The aim of this study was to evaluate the direct impact of mechanical ventilation per se on sleep quantity and quality in patients who were able to tolerate separation from mechanical ventilation over prolonged periods. DESIGN AND
settingRandomized crossover clinical trial in a medical ICU. PATIENTS: Sixteen conscious patients, free of sedation and tracheostomized because of prolonged weaning from mechanical ventilation, were included in the study when able to tolerate at least 5 hours of spontaneous ventilation.
interventionsPatients were randomized to receive either spontaneous ventilation or mechanical ventilation at low levels of pressure support for two crossover periods of 5-hour duration each, from 22:00 to 08:00. Polysomnography was performed throughout the study. MEASUREMENTS AND
resultsTotal sleep time was higher during mechanical ventilation than during spontaneous ventilation (183 min vs 132 min, p = 0.04). No significant differences between mechanical ventilation and spontaneous ventilation were observed in slow wave sleep time (45 min vs 28 min), rapid eye movement sleep time (11 min vs 3 min), or the fragmentation index (25 vs 23 arousals and awakenings per hr). In four patients, however, our analysis of patient-ventilator interaction suggested that the ventilatory settings were suboptimal and could have been improved to potentially improve sleep.
conclusionsIn difficult-to-wean tracheostomized patients, sleep quality was similar with or without the ventilator. Sleep quantity was higher during mechanical ventilation. Reconnection to the ventilator during the night period may favor sleep efficiency in tracheostomized patients in prolonged weaning.
Indexed as
Identifiers
23507721What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.