Trial reportAmerican journal of obstetrics and gynecology2013
Risk factors for uterine atony/postpartum hemorrhage requiring treatment after vaginal delivery.
Trial report in American journal of obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 6 syntheses or guidelines pooled it, 241 citations in OpenAlex.
- Mechanical and surgical interventions for treating primary postpartum haemorrhage.The Cochrane database of systematic reviews · 2020Pooled it
- Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage.The Cochrane database of systematic reviews · 2019Pooled it
- Systematic review to investigate the safety of induction and augmentation of labour among pregnant women with iron-deficiency anaemia.BMJ open · 2018Pooled it
- Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis.The Cochrane database of systematic reviews · 2018Pooled it
- Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis.The Cochrane database of systematic reviews · 2018Pooled it
- Treatment for primary postpartum haemorrhage.The Cochrane database of systematic reviews · 2014Pooled it
- Duration of the second and third stages of labor and risk of postpartum hemorrhage: a cohort study stratified by parity.BMC pregnancy and childbirth · 2025Trial
- Adverse Pregnancy Outcomes of Patients with History of First-Trimester Recurrent Spontaneous Abortion.BioMed research international · 2017Trial
- Categorizing differences in postpartum hemorrhage management and associated clinical factors.Pregnancy (Hoboken, N.J.) · 2026Article
- Estimating the incidence and risk factors of postpartum hemorrhage from the national ENACT network.npj health systems · 2026Article
- Postpartum Haemorrhage and Long-Term Mortality.Paediatric and perinatal epidemiology · 2025Article
- Postpartum obstetric complications: a guide for radiologists.Abdominal radiology (New York) · 2025Review
- The value of routine hemoglobin level evaluation following elective cesarean section: Is it worthwhile?International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Article
- Association between intravenous fluids during labor and primary postpartum hemorrhage: A retrospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- The interval between the onset of increased blood pressure and proteinuria in preeclampsia and the contributing factors.Archives of gynecology and obstetrics · 2024Article
- Recommendations for diagnosis, treatment, and prevention of iron deficiency and iron deficiency anemia.HemaSphere · 2024Article
- Prediction of post-delivery hemoglobin levels with machine learning algorithms.Scientific reports · 2024Article
- Article
- Association between duration of intrapartum oxytocin exposure and obstetric hemorrhage.Archives of gynecology and obstetrics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveWe sought to identify risk factors for uterine atony or hemorrhage. STUDY
designWe conducted a secondary analysis of a 3-arm double-blind randomized trial of different dose regimens of oxytocin to prevent uterine atony after vaginal delivery. The primary outcome was uterine atony or hemorrhage requiring treatment. In all, 21 potential risk factors were evaluated. Logistic regression was used to identify independent risk factors using 2 complementary predefined model selection strategies.
resultsAmong 1798 women randomized to 10, 40, or 80 U of prophylactic oxytocin after vaginal delivery, treated uterine atony occurred in 7%. Hispanic (odds ratio [OR], 2.1; 95% confidence interval [CI], 1.3-3.4), non-Hispanic white (OR, 1.6; 95% CI, 1.0-2.5), preeclampsia (OR, 3.2; 95% CI, 2.0-4.9), and chorioamnionitis (OR, 2.8; 95% CI, 1.6-5.0) were consistent independent risk factors. Other risk factors based on the specified selection strategies were obesity, induction/augmentation of labor, twins, hydramnios, anemia, and arrest of descent. Amnioinfusion appeared to be protective against uterine atony (OR, 0.53; 95% CI, 0.29-0.98).
conclusionIndependent risk factors for uterine atony requiring treatment include Hispanic and non-Hispanic white ethnicity, preeclampsia, and chorioamnionitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.