Evidence map›Paper›PMID 23506974›Full record

Trial reportContemporary clinical trials2013

Considering patient diet preference to optimize weight loss: design considerations of a randomized trial investigating the impact of choice.

William S Yancy, Cynthia J Coffman, Paula J Geiselman, Ronette L Kolotkin, Daniel Almirall, Eugene Z Oddone, Stephanie B Mayer, Leslie A Gaillard, Marsha Turner, Valerie A Smith and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01152359 (Considering Patient Diet Preference to Optimize Weight Loss), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01152359 nacompletednot on this map

Considering Patient Diet Preference to Optimize Weight Loss

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2011 to 2013Enrolled207ConditionsObesityArmsChoice, Control
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Design, analysis, and interpretation of treatment response heterogeneity in personalized nutrition and obesity treatment research.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023 · on this map
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

William S YancyCenter for Health Services Research in Primary Care, Department of Veterans Affairs, Durham, NC, USA. yancy006@mc.duke.edu
Cynthia J Coffman
Paula J Geiselman
Ronette L Kolotkin
Daniel Almirall
Eugene Z Oddone
Stephanie B Mayer
Leslie A Gaillard
Marsha Turner
Valerie A Smith
Corrine I Voils

Funding

THE REFINEMENT &APPLICATION OF MEDICAL DECISION MAKING IN PREVENTION SCIENCESP50DA010075 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI COFFMAN, DONNA LYNN · 1996 to 2014
$24.5M
NIDA NIH HHS P50 DA010075
6 · The paper itself

Abstract

A variety of diet approaches achieve moderate weight loss in many individuals. Yet, most diet interventions fail to achieve meaningful weight loss in more than a few individuals, likely due to inadequate adherence to the diet. It is widely conjectured that targeting the diet to an individual's food preferences will enhance adherence, thereby improving weight loss. This article describes the design considerations of a study protocol aimed at testing this hypothesis. The study is a 2-arm randomized trial recruiting 216 medical outpatients with BMI ≥30 kg/m(2) followed for 48 weeks. Participants in the experimental arm (Choice) select from two of the most widely studied diets for weight loss, a low-carbohydrate, calorie-unrestricted diet (LCD) or a low-fat, reduced-calorie diet (LFD). The participant's choice is informed by results from a validated food preference questionnaire and a discussion of diet options with trained personnel. Choice participants are given the option to switch to the other diet after three months, if desired. Participants in the Control arm are randomly assigned to follow one of the two diets for the duration of follow-up. The primary outcome is weight assessed every 2-4 weeks for 48 weeks. Secondary outcomes include adherence to diet by food frequency questionnaire and obesity-specific health-related quality of life. If assisting patients to choose their diet enhances adherence and increases weight loss, the results will support the provision of diet options to patients who desire weight loss, and bring us one step closer to remediating the obesity epidemic faced by our healthcare systems.

Indexed as

DietPatient PreferenceWeight LossCaloric RestrictionDietary CarbohydratesDietary FatsDiet, ReducingHumansPatient ComplianceQuality of LifeResearch DesignDietary CarbohydratesDietary Fats

Identifiers

PMID23506974
PMCPMC4351659

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.