ArticleBMC psychiatry2013
The prevalence of metabolic syndrome amongst patients with severe mental illness in the community in Hong Kong--a cross sectional study.
Article in BMC psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02983188 (A Double-blind, Randomized, Placebo-controlled Trial of Berberine as an Adjuvant to Treat Antipsychotic-induced Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Double-blind, Randomized, Placebo-controlled Trial of Berberine as an Adjuvant to Treat Antipsychotic-induced Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Prevalence of metabolic syndrome in Chinese patients with schizophrenia: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Recent trends in psychotropic medication use in children and adolescents in Ireland.European child & adolescent psychiatry · 2025Article
- Barriers and facilitators to detection and treatment of obstructive sleep apnoea syndrome in people with severe mental illnesses, qualitative interview study and referrer survey.BMC psychiatry · 2025Article
- Article
- Determinants and outcomes of health-promoting lifestyle among people with schizophrenia.BMC psychiatry · 2024Article
- Berberine, a Herbal Metabolite in the Metabolic Syndrome: The Risk Factors, Course, and Consequences of the Disease.Molecules (Basel, Switzerland) · 2022Review
- Prevalence and Associated Factors of Dyslipidemia Among Psychiatric Patients on Antipsychotic Treatment at Hawassa University Comprehensive Specialized Hospital.Nutrition and metabolic insights · 2021Article
- Prevalence and Associated Factors of Metabolic Syndrome Among Patients with Severe Mental Illness at Hawassa, Southern-Ethiopia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Prevalence and Associated Factors of Metabolic Syndrome among Patients with Severe Mental Illness Attending a Tertiary Hospital in Southwest Uganda.BioMed research international · 2019Article
- Prevalence of Metabolic Syndrome in the Hospitalized Psychiatric Patients.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2017Article
- Prevalence of Metabolic Syndrome among Psychiatric Inpatients: A Hospital Based Study from Kashmir.Journal of clinical and diagnostic research : JCDR · 2017Article
- Cardiometabolic health, prescribed antipsychotics and health-related quality of life in people with schizophrenia-spectrum disorders: a cross-sectional study.BMC psychiatry · 2016Observational
- Metabolic Syndrome in South African Patients with Severe Mental Illness: Prevalence and Associated Risk Factors.PloS one · 2016Article
- Metabolic syndrome in patients with severe mental illness in Gorgan.Journal of natural science, biology, and medicineArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with severe mental illness are at increased risk of developing metabolic disorders. The risk of metabolic syndrome in the Hong Kong general population is lower than that observed in western countries; however the prevalence of metabolic syndrome in patients with severe mental illness in Hong Kong is unknown.
methodThis cross-sectional study aimed to estimate the prevalence of metabolic syndrome in patients with severe mental illness in Hong Kong and to identify the relationships between metabolic syndrome and socio-demographic, clinical and lifestyle factors.
resultsA total of 139 patients with a diagnosis of severe mental illness participated in the study. The unadjusted prevalence of metabolic syndrome was 35%. The relative risk of metabolic syndrome in comparison with the general Hong Kong population was 2.008 (95% CI 1.59-2.53, p < 0.001). In a logistic regression model sleep disruption and being prescribed first generation antipsychotics were significantly associated with the syndrome, whilst eating less than 3 portions of fruit/vegetables per day and being married were weakly associated.
conclusionThe results demonstrate that metabolic syndrome is highly prevalent and that physical health inequalities in patients with severe mental illness in Hong Kong are similar to those observed in western countries. The results provide sufficient evidence to support the need for intervention studies in this setting and reinforce the requirement to conduct regular physical health checks for all patients with severe mental illness.
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