ArticlePLoS genetics2013
Polycomb group gene OsFIE2 regulates rice (Oryza sativa) seed development and grain filling via a mechanism distinct from Arabidopsis.
Article in PLoS genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 118 citations in OpenAlex.
- Rice OsMKK6-OsMPK4 cascade regulates endosperm cellularization via Polycomb Repressive Complex 2.Science China. Life sciences · 2026Article
- Translating research on seed dormancy and germination from Arabidopsis to temperate cereals to control pre-harvest sprouting.Frontiers in plant science · 2026Review
- Epigenetic control of seed development and dormancy in cereals.Plant signaling & behavior · 2025Review
- Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble network-based systems biology approach.BMC plant biology · 2025Article
- To infinity and beyond: recent progress, bottlenecks, and potential of clonal seeds by apomixis.The Plant journal : for cell and molecular biology · 2025Review
- Dynamic atlas of histone modifications and gene regulatory networks in endosperm of bread wheat.Nature communications · 2024Article
- RAL6 encodes a seed allergenic protein that positively regulates grain weight and seed germination.Journal of plant research · 2024Article
- GR5 acts in the G protein pathway to regulate grain size in rice.Plant communications · 2024Article
- Mutation in Polycomb repressive complex 2 gene OsFIE2 promotes asexual embryo formation in rice.Nature plants · 2023Article
- SLG2 specifically regulates grain width through WOX11-mediated cell expansion control in rice.Plant biotechnology journal · 2023Article
- Cytological, transcriptome and miRNome temporal landscapes decode enhancement of rice grain size.BMC biology · 2023Article
- Genome-wide identification and characterization of polycomb repressive complex 2 core components in upland cotton (Gossypium hirsutum L.).BMC plant biology · 2023Article
- Transcript profiling of Polycomb gene family in Oryza sativa indicates their abiotic stress-specific response.Functional & integrative genomics · 2022Article
- Whole-genome resequencing of the wheat A subgenome progenitor Triticum urartu provides insights into its demographic history and geographic adaptation.Plant communications · 2022Article
- Deep polygenic neural network for predicting and identifying yield-associated genes in Indonesian rice accessions.Scientific reports · 2022Article
- Histone Modification and Chromatin Remodeling During the Seed Life Cycle.Frontiers in plant science · 2022Review
- Post-Embryonic Phase Transitions Mediated by Polycomb Repressive Complexes in Plants.International journal of molecular sciences · 2021Review
- Mutation of the imprinted gene OsEMF2a induces autonomous endosperm development and delayed cellularization in rice.The Plant cell · 2021Article
- SDG711 Is Involved in Rice Seed Development through Regulation of Starch Metabolism Gene Expression in Coordination with Other Histone Modifications.Rice (New York, N.Y.) · 2021Article
- The maternally expressed polycomb group genePlant communications · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cereal endosperm represents 60% of the calories consumed by human beings worldwide. In addition, cereals also serve as the primary feedstock for livestock. However, the regulatory mechanism of cereal endosperm and seed development is largely unknown. Polycomb complex has been shown to play a key role in the regulation of endosperm development in Arabidopsis, but its role in cereal endosperm development remains obscure. Additionally, the enzyme activities of the polycomb complexes have not been demonstrated in plants. Here we purified the rice OsFIE2-polycomb complex using tandem affinity purification and demonstrated its specific H3 methyltransferase activity. We found that the OsFIE2 gene product was responsible for H3K27me3 production specifically in vivo. Genetic studies showed that a reduction of OsFIE2 expression led to smaller seeds, partially filled seeds, and partial loss of seed dormancy. Gene expression and proteomics analyses found that the starch synthesis rate limiting step enzyme and multiple storage proteins are down-regulated in OsFIE2 reduction lines. Genome wide ChIP-Seq data analysis shows that H3K27me3 is associated with many genes in the young seeds. The H3K27me3 modification and gene expression in a key helix-loop-helix transcription factor is shown to be regulated by OsFIE2. Our results suggest that OsFIE2-polycomb complex positively regulates rice endosperm development and grain filling via a mechanism highly different from that in Arabidopsis.
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