Considerations for targeting β-catenin signaling in fibrosis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed.

1. Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.Proceedings of the National Academy of Sciences of the United States of America · 2013
   Trial
2. A Multispecies, Modality-Agnostic Scalable In Vivo Mosaic Screening Platform for Therapeutic Target Discovery.bioRxiv : the preprint server for biology · 2026
   Article
3. Research progress on scar-free healing.Annals of medicine · 2025
   Review
4. EZH2 activates Wnt/β-catenin signaling in human uterine fibroids, which is inhibited by the natural compound methyl jasmonate.F&S science · 2023
   Article
5. Tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis by modulating β-catenin signaling.Nature communications · 2022
   Article
6. WNT Signalling in Lung Physiology and Pathology.Handbook of experimental pharmacology · 2021
   Article
7. The self-fulfilling prophecy of pulmonary fibrosis: a selective inspection of pathological signalling loops.The European respiratory journal · 2020
   Review
8. The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300.Cancers · 2019
   Article
9. Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein-protein interfaces of nuclear factors.British journal of pharmacology · 2017
   Review
10. Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways.Scientific reports · 2017
    Article
11. Update in diffuse parenchymal lung disease, 2013.American journal of respiratory and critical care medicine · 2015
    Article
12. Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis.American journal of respiratory and critical care medicine · 2014
    Article
13. Can we safely target the WNT pathway?Nature reviews. Drug discovery · 2014
    Review
14. Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth.Fertility and sterility · 2014
    Article
15. Inhibition of β-catenin/p300 interaction proximalizes mouse embryonic lung epithelium.Translational respiratory medicine · 2014
    Article
16. Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications.Human reproduction update
    Review

Corrections and comments

• Comment on
  β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.2013

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as