ArticleThe international journal of cardiovascular imaging2013
Computed tomography calcium score scan for attenuation correction of N-13 ammonia cardiac positron emission tomography: effect of respiratory phase and registration method.
Article in The international journal of cardiovascular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Deep Learning-Based CT-Less Cardiac Segmentation of PET Images: A Robust Methodology for Multi-Tracer Nuclear Cardiovascular Imaging.Journal of imaging informatics in medicine · 2026Article
- Best practice for the nuclear medicine technologist in CT-based attenuation correction and calcium score for nuclear cardiology.European journal of hybrid imaging · 2020Review
- Assessment of attenuation correction for myocardial PET imaging using combined PET/MRI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Extending the Use of Coronary Calcium Scanning to Clinical Rather Than Just Screening Populations: Ready for Prime Time?Circulation. Cardiovascular imaging · 2016Article
- Automatic registration of misaligned CT attenuation correction maps in Rb-82 PET/CT improves detection of angiographically significant coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Attenuation correction in cardiac PET: To raise awareness for a problem which is as old as PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Single low-dose CT scan optimized for rest-stress PET attenuation correction and quantification of coronary artery calcium.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Article
- Evaluation of whole-body MR to CT deformable image registration.Journal of applied clinical medical physics · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
The use of coronary calcium scoring (CaScCT) for attenuation correction (AC) of (13)N-ammonia PET/CT studies (NH3) is still being debated. We compare standard ACCT to CaScCT using various respiratory phases and co-registration methods for AC. Forty-one patients underwent a stress/rest NH3. Standard ACCT scans and CaScCT acquired during inspiration (CaScCTinsp, 26 patients) or expiration (CaScCTexp, 15 patients) were used to correct PET data for photon attenuation. Resulting images were compared using Pearson's correlation and Bland-Altman (BA) limits of agreement (LA) on segmental relative and absolute coronary blood flow (CBF) using both manual and automatic co-registration methods (rigid-body and deformable). For relative perfusion, CaScCTexp correlates better than CaScCTinsp with ACCT when using manual co-registration (r = 0.870; P < 0.001 and r = 0.732; P < 0.001, respectively). Automatic co-registration provides the best correlation between CaScCTexp and ACCT for relative perfusion (r = 0.956; P < 0.001). Both CaScCTinsp and CaScCTexp yielded excellent correlations with ACCT for CBF when using manual co-registration (r = 0.918; P < 0.001; BA mean bias 0.05 ml/min/g; LA: -0.42 to +0.3 ml/min/g and r = 0.97; P < 0.001; BA mean bias 0.1 ml/min/g; LA: -0.65 to +0.5 ml/min/g, respectively). The use of CaScCTexp and deformable co-registration is best suited for AC to quantify relative perfusion and CBF enabling substantial radiation dose reduction.
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Registered trials
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