ArticleFrontiers in neurology2013
Trunk orientation, stability, and quadrupedalism.
Article in Frontiers in neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Trial
- Exploring the Significance of the Obturator Externus Groove as a Marker for Bipedalism: A Cadaveric Study.Cureus · 2026Article
- Haptic communication and interpersonal dynamics in hand-by-hand guided locomotion in children and adults.Frontiers in bioengineering and biotechnology · 2025Article
- Two Sides of the Same Coin: Tendoligamentous Similarities and Dissimilarities of Great Toe and Thumb Anatomy on MRI.The Indian journal of radiology & imaging · 2022Article
- Effects of Induced Malocclusion on Vertebral Alignment in Rats: A Controlled Study by CBCTs.Animals : an open access journal from MDPI · 2021Article
- Emergence of Different Gaits in Infancy: Relationship Between Developing Neural Circuitries and Changing Biomechanics.Frontiers in bioengineering and biotechnology · 2020Review
- Muscle Responses to Passive Joint Movements in Infants During the First Year of Life.Frontiers in physiology · 2019Article
- The Influence of Dental Occlusion on Dynamic Balance and Muscular Tone.Frontiers in physiology · 2019Article
- Human Postural Control.Frontiers in neuroscience · 2018Review
- The neural control of interlimb coordination during mammalian locomotion.Journal of neurophysiology · 2017Review
- Immature Spinal Locomotor Output in Children with Cerebral Palsy.Frontiers in physiology · 2016Article
- Human locomotion under reduced gravity conditions: biomechanical and neurophysiological considerations.BioMed research international · 2014Review
- Article
- Two families with quadrupedalism, mental retardation, no speech, and infantile hypotonia (Uner Tan Syndrome Type-II); a novel theory for the evolutionary emergence of human bipedalism.Frontiers in neuroscience · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interesting cases of human quadrupedalism described by Tan and Colleagues (2005-2012) have attracted the attention of geneticists, neurologists, and anthropologists. Since his first publications in 2005, the main attention has focused on the genetic aspects of disorders that lead to quadrupedalism within an evolutionary framework. In recent years this area has undergone a convincing critique (Downey, 2010) and ended with a call "… to move in a different direction … away from thinking solely in terms of genetic abnormality and evolutionary atavism." We consider quadrupedalism as a "natural experiment" that may contribute to our knowledge of the physiological mechanisms underlying our balance system and our tendency toward normal (upright) posture. Bipedalism necessitates a number of characteristics that distinguish us from our ancestors and present-day mammals, including: size and shape of the bones of the foot, structure of the axial and proximal musculature, and the orientation of the human body and head. In this review we address the results of experimental studies on the mechanisms that stabilize the body in healthy people, as well as how these mechanisms may be disturbed in various forms of clinical pathology. These disturbances are related primarily to automatic rather than voluntary control of posture and suggest that human quadrupedalism is a behavior that can result from adaptive processes triggered by disorders in postural tone and environmental cues. These results will serve as a starting point for comparing and contrasting bi- and quadrupedalism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.