Evidence map›Paper›PMID 23503911›Full record

ArticleBrazilian journal of otorhinolaryngology

Indications and pitfalls of immunohistochemistry in head and neck cancer.

Décio de Natale Caly, Acklei Viana, Abrão Rapoport, Rogério Aparecido Dedivitis, Otávio Alberto Curioni, Cláudio Roberto Cernea, Lenine Garcia Brandão

Abstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Décio de Natale CalyHospital Heliópolis, São Paulo, Brazil.
Acklei Viana
Abrão Rapoport
Rogério Aparecido Dedivitis
Otávio Alberto Curioni
Cláudio Roberto Cernea
Lenine Garcia Brandão

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledImmunohistochemistry (IHC) has been employed in the differential diagnosis of tumors.

objectiveTo assess the use of IHC in cases of head and neck tumor.

methodThis is a retrospective study of the cases included in the Cancer Registry of the institution.

resultsIHC was used in 76 (11%) of 704 pathology tests. Most cases were carcinomas (85.80%), and 83.66% of them were squamous cell carcinomas. All tests were done with diagnostic purposes. The most frequently used antibodies were 34BE12 (37.18%), AE1/AE3 (35.9%), 35BH11 (28.21%), CD45 (25.64%), CD20 (24.36%), CD30 (24.36%), CK7 (23.08%) and CD3 (23.08%).

conclusionsIHC was used in 10.67% of the head and neck tumor cases submitted to pathology testing, mostly for carcinoma (5.26%). In the determination of squamous cell carcinoma, IHC accounted for 18.42% of all tumors.

Indexed as

ImmunohistochemistryAdultBiomarkers, TumorCarcinomaCarcinoma, Squamous CellDiagnosis, DifferentialHead and Neck NeoplasmsHumansLymphomaMiddle AgedRetrospective StudiesSarcomaBiomarkers, Tumor

Identifiers

PMID23503911
PMCPMC9450862

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.