ArticleInternational journal of colorectal disease2013
Early recurrence in patients undergoing curative surgery for colorectal cancer: is it a predictor for poor overall survival?
Article in International journal of colorectal disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 42 citations in OpenAlex.
- Perineural invasion as an independent predictor of early recurrence within 1 year after total mesorectal excision for rectal cancer.World journal of surgical oncology · 2026Article
- AAbdominal radiology (New York) · 2025Article
- Identifying timing and risk factors for early recurrence of resectable rectal cancer: A single center retrospective study.World journal of gastrointestinal surgery · 2024Article
- Post recurrence survival in early versus late period and its prognostic factors in rectal cancer patients.Scientific reports · 2024Article
- Early recurrence after complete mesocolic excision for right-sided colon cancer with D3 lymphadenectomy: pattern, risk factors, prognostic impact, and individualized follow-up.Updates in surgery · 2024Article
- Machine Learning in Diagnosis and Prognosis of Lung Cancer by PET-CT.Cancer management and research · 2024Review
- Article
- A refined prediction of early recurrence combining tumor deposits in patients with resected rectal mucinous adenocarcinoma.Surgery today · 2023Article
- Recurrence After Colectomy for Locally Advanced Colon Cancer: Experience from a Developing Country.Indian journal of surgical oncology · 2023Article
- Comparison of short-term and medium-term outcomes between intracorporeal anastomosis and extracorporeal anastomosis for laparoscopic left hemicolectomy.World journal of surgical oncology · 2022Article
- Article
- The survival after recurrence of colorectal cancer: a retrospective study focused on time to recurrence after curative resection.Surgery today · 2022Article
- Defining early recurrence of locally recurrent rectal cancer.American journal of cancer research · 2022Article
- Early Versus Late Recurrence in Rectal Cancer: Does Timing Matter?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Breast Cancer Surgery 10-Year Survival Prediction by Machine Learning: A Large Prospective Cohort Study.Biology · 2021Article
- Prognostic Factors and Treatment of Recurrence after Local Excision of Rectal Cancer.Yonsei medical journal · 2021Observational
- Shifting Treatment Strategies to Prevent Early Relapse of Locally Advanced Rectal Cancer After Preoperative Chemoradiotherapy.Annals of coloproctology · 2020Article
- Predictors of early recurrence following a curative resection in patients with a carcinoma of the ampulla of Vater.Annals of surgical treatment and research · 2020Article
- Challenges and shifting treatment strategies in the surgical treatment of locally advanced rectal cancer.Annals of gastroenterological surgery · 2020Review
- Prognostic value of serum inflammatory markers in colorectal cancer.International journal of colorectal disease · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study evaluated the prognostic value of early recurrence in patients who have undergone curative resection for colorectal cancer.
methodsA total of 1,159 consecutive patients who underwent curative resection for non-metastatic colorectal cancer from December 1998 to December 2007 were reviewed. The predictive factors for early recurrence postoperatively and the prognostic factors were analyzed.
resultsOf the 1,159 patients, postoperative recurrence was identified in 280 (24.1%) patients, and 96 (34.3%) of the 280 patients with recurrence were designed as early recurrence (less than 1 year postoperatively). In multivariate analysis, tumor location, tumor diameter, number of retrieved lymph nodes, and lymphovascular invasion were the independent predictors for early recurrence. The early recurrence group had a significantly lower overall survival rate than that of the non-early recurrence group for both colon cancer (P < 0.001) and rectal cancer (P < 0.001). The overall survival rate for stage III tumors significantly differed between the early and non-early recurred patients (P < 0.001), whereas the rate did not differ between the patients with stage II tumors (P = 0.364). In multivariate analysis, early recurrence was an independent predictor for unfavorable overall survival. Moreover, differentiation, N category, and postoperative chemotherapy were the independent predictors for overall survival for the patients with both early and overall recurrence.
conclusionPoor survival was associated with early postoperative recurrence for patients who underwent curative resection for colorectal cancer. The use of adjuvant chemotherapy prolonged the survival of patients, irrespective of the interval of recurrence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.