ArticleNature methods2013
Barcoding cells using cell-surface programmable DNA-binding domains.
Article in Nature methods, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 51 citations in OpenAlex.
- Monitoring in vivo transcription with synthetic serum markers.Nature communications · 2026Article
- Simple, Affordable, and Modular Patterning of Cells using DNA.Journal of visualized experiments : JoVE · 2021Article
- Multiplexed optical barcoding of cellsChemical science · 2021Article
- Molecular underpinnings of ssDNA specificity by Rep HUH-endonucleases and implications for HUH-tag multiplexing and engineering.Nucleic acids research · 2021Article
- Decorating bacteria with self-assembled synthetic receptors.Nature communications · 2020Article
- Lipid-Oligonucleotide Conjugates for Simple and Efficient Cell Membrane Engineering and Bioanalysis.Current opinion in biomedical engineering · 2020Article
- Crystal structure of the Wheat dwarf virus Rep domain.Acta crystallographica. Section F, Structural biology communications · 2019Article
- DNA Nanotechnology Enters Cell Membranes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Review
- Nucleic Acid-Barcoding Technologies: Converting DNA Sequencing into a Broad-Spectrum Molecular Counter.Angewandte Chemie (International ed. in English) · 2019Review
- Oligonucleotide conjugated multi-functional adeno-associated viruses.Scientific reports · 2018Article
- Sequence-Directed Covalent Protein-DNA Linkages in a Single Step Using HUH-Tags.Journal of the American Chemical Society · 2017Article
- Addressing the ethical issues raised by synthetic human entities with embryo-like features.eLife · 2017Article
- Omics approaches to individual variation: modeling networks and the virtual patient.Dialogues in clinical neuroscience · 2016Article
- Genomic and Epigenomic Alterations in Cancer.The American journal of pathology · 2016Review
- Article
- A Barcoding Strategy Enabling Higher-Throughput Library Screening by Microscopy.ACS synthetic biology · 2015Article
- Therapeutic genome editing: prospects and challenges.Nature medicine · 2015Review
- Article
- Stochastic particle barcoding for single-cell tracking and multiparametric analysis.Small (Weinheim an der Bergstrasse, Germany) · 2015Article
- Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
We report an approach to barcode cells through cell-surface expression of programmable zinc-finger DNA-binding domains (surface zinc fingers, sZFs). We show that sZFs enable sequence-specific labeling of living cells by dsDNA, and we develop a sequential labeling approach to image more than three cell types in mixed populations using three fluorophores. We demonstrate the versatility of sZFs through applications in which they serve as surrogate reporters, function as selective cell capture reagents and facilitate targeted cellular delivery of viruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.