ArticleJournal of the American College of Cardiology2013
Heart failure–associated hospitalizations in the United States.
Article in Journal of the American College of Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04828070 (The Heart Outcomes in Pregnancy Expectations), which is not on this map. Cited by 194 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Heart Outcomes in Pregnancy Expectations (H.O.P.E) Registry Pilot
Who cites it
194 citing papers in PubMed, 9 syntheses or guidelines pooled it, 386 citations in OpenAlex.
- Cimlanod, a Second-Generation Nitroxyl Donor, in Heart Failure with Reduced Ejection Fraction: A Meta-Analysis of Hemodynamic Efficacy and Safety Profile.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026Pooled it
- Incidence and influencing factors of 30-day unplanned readmission in chronic heart failure patients: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Clinical and cost-effectiveness of left ventricular assist devices as destination therapy for advanced heart failure: systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2024Pooled it
- Integrating palliative care and heart failure: a systematic realist synthesis (PalliatHeartSynthesis).Open heart · 2023Pooled it
- Efficacy and safety of catheter-based renal denervation for heart failure with reduced ejection fraction: a systematic review and meta-analysis.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2020Pooled it
- Systematic review of economic burden of heart failure.Heart failure reviews · 2018Pooled it
- Efficacy and safety of bone marrow cell transplantation for chronic ischemic heart disease: a meta-analysis.Medical science monitor : international medical journal of experimental and clinical research · 2014Pooled it
- Validity of heart failure diagnoses in administrative databases: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Caregiver Well-being and Patient Outcomes in Heart Failure: A Meta-analysis.The Journal of cardiovascular nursingPooled it
- Diuretic resistance and the efficacy of hydrochlorothiazide in acute decompensated heart failure: A post-hoc analysis of the CLOROTIC trial.European journal of heart failure · 2025Trial
- Pulmonary artery pressure-guided heart failure management: US cost-effectiveness analyses using the results of the CHAMPION clinical trial.European journal of heart failure · 2017Trial
- Trial
- Correlates of quality of life in rural patients with heart failure.Circulation. Heart failure · 2014Trial
- Endomyocardial implantation of autologous bone marrow mononuclear cells in advanced ischemic heart failure: a randomized placebo-controlled trial (END-HF).Journal of cardiovascular translational research · 2014Trial
- Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial.European heart journal · 2013Trial
- Lycopene dietary intervention: a pilot study in patients with heart failure.The Journal of cardiovascular nursingTrial
- Cardio-hepatic injury phenotypes and short-term outcomes in acute decompensated heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Early discharge after clinical stabilization in acute decompensated heart failure: associations with short-term outcomes.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Ultrasound-guided management in heart failure: A systematic review and meta-analysis evaluating lung and inferior vena cava ultrasound for reducing readmissions and mortality.American heart journal plus : cardiology research and practice · 2026Article
- Prediction of Risk of Unplanned Readmission or Death in Elderly Heart Failure Patients During the Vulnerable Phase: Machine Learning With SHAP Interpretation.FASEB bioAdvances · 2026Article
134 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesThis study sought to characterize temporal trends in hospitalizations with heart failure as a primary or secondary diagnosis.
backgroundHeart failure patients are frequently admitted for both heart failure and other causes.
methodsUsing the Nationwide Inpatient Sample (NIS), we evaluated trends in heart failure hospitalizations between 2001 and 2009. Hospitalizations were categorized as either primary or secondary heart failure hospitalizations based on the location of heart failure in the discharge diagnosis. National estimates were calculated using the sampling weights of the NIS. Age- and sex-standardized hospitalization rates were determined by dividing the number of hospitalizations by the U.S. population in a given year and using direct standardization.
resultsThe number of primary heart failure hospitalizations in the United States decreased from 1,137,944 in 2001 to 1,086,685 in 2009, whereas secondary heart failure hospitalizations increased from 2,753,793 to 3,158,179 over the same period. Age- and sex-adjusted rates of primary heart failure hospitalizations decreased steadily from 2001 to 2009, from 566 to 468 per 100,000 people. Rates of secondary heart failure hospitalizations initially increased from 1,370 to 1,476 per 100,000 people from 2001 to 2006, then decreased to 1,359 per 100,000 people in 2009. Common primary diagnoses for secondary heart failure hospitalizations included pulmonary disease, renal failure, and infections.
conclusionsAlthough primary heart failure hospitalizations declined, rates of hospitalizations with a secondary diagnosis of heart failure were stable in the past decade. Strategies to reduce the high burden of hospitalizations of heart failure patients should include consideration of both cardiac disease and noncardiac conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.