ArticleThe American journal of pathology1990
Relationship between high-grade lymphoma and low-grade B-cell mucosa-associated lymphoid tissue lymphoma (MALToma) of the stomach.
Article in The American journal of pathology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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Who cites it
47 citing papers in PubMed, 315 citations in OpenAlex.
- The new German evidence-based guideline on diffuse large B-cell lymphoma-key aspects for radiation oncologists.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023Review
- Forward and Reverse Genetics of B Cell Malignancies: From Insertional Mutagenesis to CRISPR-Cas.Frontiers in immunology · 2021Review
- Clonal relationship of marginal zone lymphoma and diffuse large B-cell lymphoma in Sjogren's syndrome patients: case series study and review of the literature.Rheumatology international · 2020Review
- Prognostic significance of helicobacter pylori-infection in gastric diffuse large B-cell lymphoma.BMC cancer · 2019Article
- Transformed mucosa-associated lymphoid tissue lymphomas: A single institution retrospective study including polymerase chain reaction-based clonality analysis.British journal of haematology · 2019Article
- Helicobacter pylori eradication in gastric diffuse large B cell lymphoma.World journal of gastroenterology · 2015Review
- Molecular Pathogenesis of MALT Lymphoma.Gastroenterology research and practice · 2015Review
- Helicobacter pylori-related diffuse large B-cell lymphoma of the stomach: a distinct entity with lower aggressiveness and higher chemosensitivity.Blood cancer journal · 2014Article
- Immunoglobulin gene repertoire diversification and selection in the stomach - from gastritis to gastric lymphomas.Frontiers in immunology · 2014Article
- Detection of the Helicobacter pylori CagA protein in gastric mucosa-associated lymphoid tissue lymphoma cells: clinical and biological significance.Blood cancer journal · 2013Article
- Two Cases of Diffuse Large B-Cell Lymphomas in the Cervical Lymph Nodes in Patients with Low-Grade Gastric Marginal Zone B-Cell Lymphoma (MALT Lymphoma).Clinical endoscopy · 2013Article
- Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass.Case reports in oncology · 2012Article
- Article
- Translocation t(11;18)(q21;q21) in gastric B-cell lymphomas.Cancer science · 2009Article
- Primary extranodal lymphomas of stomach: clinical presentation, diagnostic pitfalls and management.Annals of oncology : official journal of the European Society for Medical Oncology · 2008Review
- Therapy of gastric mucosa associated lymphoid tissue lymphoma.World journal of gastroenterology · 2007Review
- Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists.Journal of clinical pathology · 2007Review
- Current status of gastric MALT lymphoma.Current gastroenterology reports · 2006Review
- Review
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The distinctive low-grade B-cell mucosa-associated lymphoid tissue lymphoma (MALToma) of the stomach has been well characterized in recent years, but its relationship with the more commonly occurring large B-cell gastric lymphoma has not been clarified. This study aimed to elucidate their relationship. Among 48 consecutive cases of primary malignant lymphoma found in gastrectomy specimens, there were 10 cases showing coexistence of these two elements, which were further studied in detail. The high-grade component predominated in six cases, the low-grade component predominated in two cases, and the two components were intermingled in two cases. In the low-grade component, the small neoplastic cells possessed irregular nuclei (centrocytelike), and glandular invasion was a prominent feature. In the high-grade component, the blasts occurred in clusters or sheets, and often possessed plasmacytoid cytoplasm; glandular invasion was a rare event. In both components, the neoplastic cells frequently showed formation of nodules suggestive of colonization of reactive lymphoid follicles. Immunohistochemical studies showed that the neoplastic cells in the low- and high-grade components expressed the same class of immunoglobulin light chain in eight of the nine cases studied; staining in one case was unsatisfactory. Their intimate relationship as well as identical light chain restriction suggests that the high-grade component arises through blastic transformation of the low-grade component.
Indexed as
Identifiers
2349966PMC1877419W1536496525What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.