Evidence map›Paper›PMID 23499326›Full record

ArticleThe American journal of medicine2013

Functional disability, cognitive impairment, and depression after hospitalization for pneumonia.

Dimitry S Davydow, Catherine L Hough, Deborah A Levine, Kenneth M Langa, Theodore J Iwashyna

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in The American journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06644690 (The Effect of a Creative Dance-Supported CO-OP Approach on Executive Functions, Attention, Memory, and Dual-Task Performance in Older Adults With Mild Cognitive Impairment), which is not on this map. Cited by 86 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06644690 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effect of a Creative Dance-Supported CO-OP Approach on Executive Functions, Attention, Memory, and Dual-Task Performance in Older Adults With Mild Cognitive Impairment: A Randomized Controlled Trial

TypeinterventionalSponsorÇankırı Karatekin UniversityRan2024 to 2025Enrolled26ConditionsMild Cognitive Impairment (MCI)ArmsCO-OP with Creative Dance, CO-OP Only
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Exercise for acutely hospitalised older medical patients.The Cochrane database of systematic reviews · 2022
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dimitry S DavydowDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104, USA. ddavydo1@u.washington.edu
Catherine L Hough
Deborah A Levine
Kenneth M Langa
Theodore J Iwashyna

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Institute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6M
The Cost of DementiaR01AG030155 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 2007 to 2011
$3.1M
The structure and outcomes of critical care transfer networkK08HL091249 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IWASHYNA, THEODORE J · 2008 to 2012
$661k
The Predictors and Long-Term Trajectory of Poststroke Cognitive DeclineK23AG040278 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEVINE, DEBORAH ALLISON · 2012 to 2015
$637k
NCATS NIH HHS KL2 TR000421NHLBI NIH HHS K08 HL091249NIA NIH HHS K23 AG040278NIA NIH HHS R01 AG030155NIA NIH HHS U01 AG009740NIA NIH HHS U01 AG09740
6 · The paper itself

Abstract

objectiveThe study objective was to examine whether hospitalization for pneumonia is associated with functional decline, cognitive impairment, and depression, and to compare this impairment with that seen after known disabling conditions, such as myocardial infarction or stroke.

methodsWe used data from a prospective cohort of 1434 adults aged more than 50 years who survived 1711 hospitalizations for pneumonia, myocardial infarction, or stroke drawn from the Health and Retirement Study (1998-2010). Main outcome measures included the number of Activities and Instrumental Activities of Daily Living requiring assistance and the presence of cognitive impairment and substantial depressive symptoms.

resultsHospitalization for pneumonia was associated with 1.01 new impairments in Activities and Instrumental Activities of Daily Living (95% confidence interval [CI], 0.71-1.32) among patients without baseline functional impairment and 0.99 new impairments in Activities and Instrumental Activities of Daily Living (95% CI, 0.57-1.41) among those with mild-to-moderate baseline limitations, as well as moderate-to-severe cognitive impairment (odds ratio, 2.46; 95% CI, 1.60-3.79) and substantial depressive symptoms (odds ratio, 1.63; 95% CI, 1.06-2.51). Patients without baseline functional impairment who survived pneumonia hospitalization had more subsequent impairments in Activities and Instrumental Activities of Daily Living than those who survived myocardial infarction hospitalization. There were no significant differences in subsequent moderate-to-severe cognitive impairment or substantial depressive symptoms between patients who survived myocardial infarction or stroke and those who survived pneumonia.

conclusionsHospitalization for pneumonia in older adults is associated with subsequent functional and cognitive impairment. Improved pneumonia prevention and interventions to ameliorate adverse sequelae during and after hospitalization may improve outcomes.

Indexed as

Activities of Daily LivingAgedAged, 80 and overCognitive DysfunctionDepressionHospitalizationHumansLogistic ModelsLongitudinal StudiesMiddle AgedMyocardial InfarctionPneumoniaStroke

Identifiers

PMID23499326
PMCPMC3690157

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.