Evidence map›Paper›PMID 23498938›Full record

ReviewCell2013

Long noncoding RNAs: cellular address codes in development and disease.

Pedro J Batista, Howard Y Chang

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,550 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,550citing papers in PubMed, 2 pooled it
54.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,550 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2,635 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Long Noncoding RNANon-coding RNA · 2026
    Article
  6. Review
  7. Article
  8. Comparative Effects ofInternational journal of molecular sciences · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. ComprehensiveNon-coding RNA · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

1,490 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pedro J BatistaHoward Hughes Medical Institute and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Howard Y Chang
Howard Hughes Medical Institute · US

Funding

Structural Motifs in RNAR01HG004361 · NHGRI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2007 to 2018
$4.7M
Wound Response Genes in Cancer ProgressionR01CA118750 · NCI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2007 to 2016
$2.9M
Howard Hughes Medical InstituteNCI NIH HHS R01 CA118750NHGRI NIH HHS R01 HG004361
6 · The paper itself

Abstract

In biology as in real estate, location is a cardinal organizational principle that dictates the accessibility and flow of informational traffic. An essential question in nuclear organization is the nature of the address code--how objects are placed and later searched for and retrieved. Long noncoding RNAs (lncRNAs) have emerged as key components of the address code, allowing protein complexes, genes, and chromosomes to be trafficked to appropriate locations and subject to proper activation and deactivation. lncRNA-based mechanisms control cell fates during development, and their dysregulation underlies some human disorders caused by chromosomal deletions and translocations.

Indexed as

AnimalsCell NucleusDiseaseGene Expression RegulationHumansRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID23498938
PMCPMC3651923
OpenAlexW1970741980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.