Evidence map›Paper›PMID 23497744›Full record

ReviewAutonomic neuroscience : basic & clinical2013

Cardiorespiratory coupling in health and disease.

Alfredo J Garcia, Jenna E Koschnitzky, Tatiana Dashevskiy, Jan-Marino Ramirez

Registry-linked trialAbstract readReview
In one paragraph

Review in Autonomic neuroscience : basic & clinical, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02441192 (Cardiovascular and Cardiorespiratory Coupling After Different Types of Training and Detraining), which is not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02441192 nacompletednot on this map

Cardiovascular and Cardiorespiratory Coupling After Different Types of Training and Detraining

TypeinterventionalSponsorUniversity of BarcelonaRan2013 to 2015Enrolled40ConditionsHealth BehaviorArmsTraining resistance, Training aerobic, Training resistance+aerobic
3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

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  9. How causal is "circular causality"?Frontiers in network physiology · 2026
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  12. Review
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  16. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alfredo J GarciaCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.
Jenna E Koschnitzky
Tatiana Dashevskiy
Jan-Marino Ramirez

Funding

Integrative Consequences of HypoxiaP01HL090554 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2008 to 2017
$21.4M
Mechanisms underlying neuromodulation-induced breathing instabilityR01HL107084 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI RAMIREZ, JAN M. · 2011 to 2014
$2.6M
NHLBI NIH HHS P01 HL090554NHLBI NIH HHS R01 HL107084
6 · The paper itself

Abstract

Cardiac and respiratory activities are intricately linked both functionally as well as anatomically through highly overlapping brainstem networks controlling these autonomic physiologies that are essential for survival. Cardiorespiratory coupling (CRC) has many potential benefits creating synergies that promote healthy physiology. However, when such coupling deteriorates autonomic dysautonomia may ensue. Unfortunately there is still an incomplete mechanistic understanding of both normal and pathophysiological interactions that respectively give rise to CRC and cardiorespiratory dysautonomia. Moreover, there is also a need for better quantitative methods to assess CRC. This review addresses the current understanding of CRC by discussing: (1) the neurobiological basis of respiratory sinus arrhythmia (RSA); (2) various disease states involving cardiorespiratory dysautonomia; and (3) methodologies measuring heart rate variability and RSA.

Indexed as

Cardiovascular Physiological PhenomenaRespiratory Physiological PhenomenaAnimalsAutonomic Nervous SystemAutonomic Nervous System DiseasesHumans

Identifiers

PMID23497744
PMCPMC3683976

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.